27-Hydroxycholesterol in cancer development and drug resistance
27-Hydroxycholesterol (27HC), a cholesterol metabolite, functions both as a selective oestrogen receptor (ER) modulator and a ligand for liver X receptors (LXRs). The discovery of 27HC involvement in carcinogenesis has unveiled new research avenues, yet its precise role remains controversial and con...
Saved in:
| Main Authors: | Yaxin Hou, Zhiguang Fu, Chenhui Wang, Paulina Kucharzewska, Yuan Guo, Sihe Zhang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2025-12-01
|
| Series: | Journal of Enzyme Inhibition and Medicinal Chemistry |
| Subjects: | |
| Online Access: | https://www.tandfonline.com/doi/10.1080/14756366.2025.2507670 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
NPC1L1 Drives Osteoporosis by Activating the C/EBPα/Cyp27a1/27‐Hydroxycholesterol Axis: A Novel Therapeutic Target for Bone Loss
by: Bohao Li, et al.
Published: (2025-06-01) -
Associations between plasma 24(S)-hydroxycholesterol and neuropsychological profile in fragile X syndrome
by: Asma Laroui, et al.
Published: (2025-05-01) -
The Cross-Talk Between the Peripheral and Brain Cholesterol Metabolisms
by: Ilinca Savulescu-Fiedler, et al.
Published: (2025-02-01) -
Toxoplasma gondii-induced host’s high secretion of 25-hydroxycholesterol for immunoprotection
by: Zi-Han Yang, et al.
Published: (2025-08-01) -
Role of oxysterol 4β-hydroxycholesterol and liver X receptor alleles in pre-eclampsia
by: Lassi Kaartinen, et al.
Published: (2025-12-01)