Preventing the rejection of skin allografts by immunomodulatory and regenerative effects of exosomes derived from bone marrow mesenchymal stem cells in mice

Preventing the rejection of skin allografts by immunomodulatory and regenerative effects of exosomes derived from bone marrow mesenchymal stem cells in mice

Objective(s): Reducing the immune response to inflammation is vital for successful transplantation, yet chronic graft rejection remains a major issue despite immunosuppressive drugs. This study explored the effect of bone marrow mesenchymal stem cell-derived exosomes on the survival of skin allograf...

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Bibliographic Details
Main Authors: Parham Soufizadeh, Gholamreza Nikbakht Brujeni, Mohammad Mehdi Dehghan, Massoumeh Jabbari Fakhr, Pouya Houshmand, Mahyar Mohebbi, Hossein Aminianfar, Sirous Sadeghian Chaleshtori
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2025-04-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
exosome
immunomodulation
mice
mesenchymal stem cells
regeneration
transplantation
Online Access:https://ijbms.mums.ac.ir/article_25466_d9fc76c98b3d0c137d91269d1ae77034.pdf
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