Adhesive lipophilic gels delivering rapamycin prevent oral leukoplakia from malignant transformation

Adhesive lipophilic gels delivering rapamycin prevent oral leukoplakia from malignant transformation

Oral leukoplakia (OLK) is the most emblematic oral potentially malignant disorder that may precede the diagnosis of oral squamous cell carcinoma (OSCC) and has an overall malignant transformation rate of 9.8 %. Early intervention is crucial to reduce the malignant transformation rate from OLK to OSC...

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Bibliographic Details
Main Authors: Yuqi Du, Tiannan Liu, Tingting Ding, Xin Zeng, Qianming Chen, Hang Zhao
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Materials Today Bio
Subjects:
Oral leukoplakia
Rapamycin
Malignant transformation
Hydrogels
Drug delivery systems
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006424003661
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