A case of hereditary alpha tryptasemia and presumptive eosinophilic granulomatosis with polyangiitis
This case is notable for the potential overlap of hereditary alpha tryptasemia and eosinophilic granulomatosis with polyangiitis. The successful use of mepolizumab, initially for eosinophilic granulomatosis with polyangiitis but potentially benefiting the patient's hereditary alpha tryptasemia,...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-08-01
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| Series: | Journal of Allergy and Clinical Immunology: Global |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772829325000827 |
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| author | Sonia Iqbal, DO Joseph A. Baxter, DO Karla E. Adams, MD |
| author_facet | Sonia Iqbal, DO Joseph A. Baxter, DO Karla E. Adams, MD |
| author_sort | Sonia Iqbal, DO |
| collection | DOAJ |
| description | This case is notable for the potential overlap of hereditary alpha tryptasemia and eosinophilic granulomatosis with polyangiitis. The successful use of mepolizumab, initially for eosinophilic granulomatosis with polyangiitis but potentially benefiting the patient's hereditary alpha tryptasemia, offers a novel approach to managing complex cases involving both rare disorders. |
| format | Article |
| id | doaj-art-2c3e463d885b4e4d90f670277ae27413 |
| institution | DOAJ |
| issn | 2772-8293 |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Allergy and Clinical Immunology: Global |
| spelling | doaj-art-2c3e463d885b4e4d90f670277ae274132025-08-20T03:00:25ZengElsevierJournal of Allergy and Clinical Immunology: Global2772-82932025-08-014310048110.1016/j.jacig.2025.100481A case of hereditary alpha tryptasemia and presumptive eosinophilic granulomatosis with polyangiitisSonia Iqbal, DO0Joseph A. Baxter, DO1Karla E. Adams, MD2Department of Internal Medicine, Malcolm Grow Medical Center, Joint Base Andrews, Md; Corresponding author: Sonia Iqbal, DO, Malcolm Grow Medical Center, 1060 W Perimeter Rd, Joint Base Andrews, MD 20762.Department of Allergy and Immunology, 56th Medical Group, Luke Air Force Base, ArizDepartment of Allergy and Immunology, Wilford Hall Ambulatory Surgical Center, Lackland Air Force Base, TexThis case is notable for the potential overlap of hereditary alpha tryptasemia and eosinophilic granulomatosis with polyangiitis. The successful use of mepolizumab, initially for eosinophilic granulomatosis with polyangiitis but potentially benefiting the patient's hereditary alpha tryptasemia, offers a novel approach to managing complex cases involving both rare disorders.http://www.sciencedirect.com/science/article/pii/S2772829325000827Hereditary alpha tryptasemiaeosinophilic granulomatosis with polyangiitishypereosinophiliamepolizumabelevated tryptase level |
| spellingShingle | Sonia Iqbal, DO Joseph A. Baxter, DO Karla E. Adams, MD A case of hereditary alpha tryptasemia and presumptive eosinophilic granulomatosis with polyangiitis Journal of Allergy and Clinical Immunology: Global Hereditary alpha tryptasemia eosinophilic granulomatosis with polyangiitis hypereosinophilia mepolizumab elevated tryptase level |
| title | A case of hereditary alpha tryptasemia and presumptive eosinophilic granulomatosis with polyangiitis |
| title_full | A case of hereditary alpha tryptasemia and presumptive eosinophilic granulomatosis with polyangiitis |
| title_fullStr | A case of hereditary alpha tryptasemia and presumptive eosinophilic granulomatosis with polyangiitis |
| title_full_unstemmed | A case of hereditary alpha tryptasemia and presumptive eosinophilic granulomatosis with polyangiitis |
| title_short | A case of hereditary alpha tryptasemia and presumptive eosinophilic granulomatosis with polyangiitis |
| title_sort | case of hereditary alpha tryptasemia and presumptive eosinophilic granulomatosis with polyangiitis |
| topic | Hereditary alpha tryptasemia eosinophilic granulomatosis with polyangiitis hypereosinophilia mepolizumab elevated tryptase level |
| url | http://www.sciencedirect.com/science/article/pii/S2772829325000827 |
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