Susceptibility of livestock to SARS-CoV-2 infection

We report pilot studies to evaluate the susceptibility of common domestic livestock (cattle, sheep, goat, alpaca, rabbit, and horse) to intranasal infection with SARS-CoV-2. None of the infected animals shed infectious virus via nasal, oral, or faecal routes, although viral RNA was detected in sever...

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Main Authors: Angela M. Bosco-Lauth, Audrey Walker, Lauren Guilbert, Stephanie Porter, Airn Hartwig, Emma McVicker, Helle Bielefeldt-Ohmann, Richard A. Bowen
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Emerging Microbes and Infections
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2021.2003724
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author Angela M. Bosco-Lauth
Audrey Walker
Lauren Guilbert
Stephanie Porter
Airn Hartwig
Emma McVicker
Helle Bielefeldt-Ohmann
Richard A. Bowen
author_facet Angela M. Bosco-Lauth
Audrey Walker
Lauren Guilbert
Stephanie Porter
Airn Hartwig
Emma McVicker
Helle Bielefeldt-Ohmann
Richard A. Bowen
author_sort Angela M. Bosco-Lauth
collection DOAJ
description We report pilot studies to evaluate the susceptibility of common domestic livestock (cattle, sheep, goat, alpaca, rabbit, and horse) to intranasal infection with SARS-CoV-2. None of the infected animals shed infectious virus via nasal, oral, or faecal routes, although viral RNA was detected in several animals. Further, neutralizing antibody titres were low or non-existent one month following infection. These results suggest that domestic livestock are unlikely to contribute to SARS-CoV-2 epidemiology.
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publishDate 2021-01-01
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series Emerging Microbes and Infections
spelling doaj-art-2c23fe56e936487299cb9ad4e94e22312025-08-20T02:24:46ZengTaylor & Francis GroupEmerging Microbes and Infections2222-17512021-01-011012199220110.1080/22221751.2021.2003724Susceptibility of livestock to SARS-CoV-2 infectionAngela M. Bosco-Lauth0Audrey Walker1Lauren Guilbert2Stephanie Porter3Airn Hartwig4Emma McVicker5Helle Bielefeldt-Ohmann6Richard A. Bowen7Department of Biomedical Sciences, Colorado State University, Fort Collins, CO, USADepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO, USADepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO, USADepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO, USADepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO, USADepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO, USASchool of Chemistry & Molecular Biosciences and Australian Infectious Diseases Research Centre, The University of Queensland, St Lucia, AustraliaDepartment of Biomedical Sciences, Colorado State University, Fort Collins, CO, USAWe report pilot studies to evaluate the susceptibility of common domestic livestock (cattle, sheep, goat, alpaca, rabbit, and horse) to intranasal infection with SARS-CoV-2. None of the infected animals shed infectious virus via nasal, oral, or faecal routes, although viral RNA was detected in several animals. Further, neutralizing antibody titres were low or non-existent one month following infection. These results suggest that domestic livestock are unlikely to contribute to SARS-CoV-2 epidemiology.https://www.tandfonline.com/doi/10.1080/22221751.2021.2003724SARS-CoV-2livestockcattlesheepgoatalpaca
spellingShingle Angela M. Bosco-Lauth
Audrey Walker
Lauren Guilbert
Stephanie Porter
Airn Hartwig
Emma McVicker
Helle Bielefeldt-Ohmann
Richard A. Bowen
Susceptibility of livestock to SARS-CoV-2 infection
Emerging Microbes and Infections
SARS-CoV-2
livestock
cattle
sheep
goat
alpaca
title Susceptibility of livestock to SARS-CoV-2 infection
title_full Susceptibility of livestock to SARS-CoV-2 infection
title_fullStr Susceptibility of livestock to SARS-CoV-2 infection
title_full_unstemmed Susceptibility of livestock to SARS-CoV-2 infection
title_short Susceptibility of livestock to SARS-CoV-2 infection
title_sort susceptibility of livestock to sars cov 2 infection
topic SARS-CoV-2
livestock
cattle
sheep
goat
alpaca
url https://www.tandfonline.com/doi/10.1080/22221751.2021.2003724
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AT airnhartwig susceptibilityoflivestocktosarscov2infection
AT emmamcvicker susceptibilityoflivestocktosarscov2infection
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