Systemic inflammation accelerates the development of focal segmental glomerulosclerosis in a mouse model of adriamycin induced nephrosis

Systemic inflammation accelerates the development of focal segmental glomerulosclerosis in a mouse model of adriamycin induced nephrosis

Abstract Research indicates that minimal change disease (MCD) and focal segmental glomerulosclerosis (FSGS) may reflect varying severities of the same underlying condition, with inflammation potentially facilitating the progression from MCD to FSGS. The aim of this study was to determine the whether...

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Bibliographic Details
Main Authors: Lian Liu, Qiu Li, Gaofu Zhang
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:Scientific Reports
Subjects:
Systemic inflammation
Adriamycin-induced nephrosis
Focal segmental glomerulonephritis
Minimal change nephrotic syndrome
Online Access:https://doi.org/10.1038/s41598-025-96125-0
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