Mutation of isocitrate dehydrogenase indicates favorable outcomes in pan-cancer immune checkpoint blockade

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Bibliographic Details
Main Authors: Zhiyang Huang, Yingying Li, Hong Zhao, Bin Zhao
Format: Article
Language:English
Published: BMC 2025-02-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-025-06170-6
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author Zhiyang Huang
Yingying Li
Hong Zhao
Bin Zhao
author_facet Zhiyang Huang
Yingying Li
Hong Zhao
Bin Zhao
author_sort Zhiyang Huang
collection DOAJ
format Article
id doaj-art-2c0f6887083d470eb2410fd721e92d7f
institution Kabale University
issn 1479-5876
language English
publishDate 2025-02-01
publisher BMC
record_format Article
series Journal of Translational Medicine
spelling doaj-art-2c0f6887083d470eb2410fd721e92d7f2025-02-09T12:52:19ZengBMCJournal of Translational Medicine1479-58762025-02-012311410.1186/s12967-025-06170-6Mutation of isocitrate dehydrogenase indicates favorable outcomes in pan-cancer immune checkpoint blockadeZhiyang Huang0Yingying Li1Hong Zhao2Bin Zhao3Quanzhou First Hospital Affiliated to Fujian Medical UniversityQuanzhou First Hospital Affiliated to Fujian Medical UniversityThe Cancer Center of The Fifth Affiliated Hospital of Sun Yat-Sen UniversityQuanzhou First Hospital Affiliated to Fujian Medical Universityhttps://doi.org/10.1186/s12967-025-06170-6Isocitrate dehydrogenaseCancerImmune checkpoint blockadeBiomarker
spellingShingle Zhiyang Huang
Yingying Li
Hong Zhao
Bin Zhao
Mutation of isocitrate dehydrogenase indicates favorable outcomes in pan-cancer immune checkpoint blockade
Journal of Translational Medicine
Isocitrate dehydrogenase
Cancer
Immune checkpoint blockade
Biomarker
title Mutation of isocitrate dehydrogenase indicates favorable outcomes in pan-cancer immune checkpoint blockade
title_full Mutation of isocitrate dehydrogenase indicates favorable outcomes in pan-cancer immune checkpoint blockade
title_fullStr Mutation of isocitrate dehydrogenase indicates favorable outcomes in pan-cancer immune checkpoint blockade
title_full_unstemmed Mutation of isocitrate dehydrogenase indicates favorable outcomes in pan-cancer immune checkpoint blockade
title_short Mutation of isocitrate dehydrogenase indicates favorable outcomes in pan-cancer immune checkpoint blockade
title_sort mutation of isocitrate dehydrogenase indicates favorable outcomes in pan cancer immune checkpoint blockade
topic Isocitrate dehydrogenase
Cancer
Immune checkpoint blockade
Biomarker
url https://doi.org/10.1186/s12967-025-06170-6
work_keys_str_mv AT zhiyanghuang mutationofisocitratedehydrogenaseindicatesfavorableoutcomesinpancancerimmunecheckpointblockade
AT yingyingli mutationofisocitratedehydrogenaseindicatesfavorableoutcomesinpancancerimmunecheckpointblockade
AT hongzhao mutationofisocitratedehydrogenaseindicatesfavorableoutcomesinpancancerimmunecheckpointblockade
AT binzhao mutationofisocitratedehydrogenaseindicatesfavorableoutcomesinpancancerimmunecheckpointblockade