Manipulation of Cell Cycle and Chromatin Configuration by Means of Cell-Penetrating Geminin.

Manipulation of Cell Cycle and Chromatin Configuration by Means of Cell-Penetrating Geminin.

Geminin regulates chromatin remodeling and DNA replication licensing which play an important role in regulating cellular proliferation and differentiation. Transcription of the Geminin gene is regulated via an E2F-responsive region, while the protein is being closely regulated by the ubiquitin-prote...

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Main Authors: Yoshinori Ohno, Kyoko Suzuki-Takedachi, Shin'ichiro Yasunaga, Toshiaki Kurogi, Mimoko Santo, Yoshikazu Masuhiro, Shigemasa Hanazawa, Motoaki Ohtsubo, Kazuhito Naka, Yoshihiro Takihara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0155558&type=printable
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