Localization of Solutions to Equations of Tumor Dynamics

This article discusses a mathematical model of tumor dynamics. The tissue is considered as a multiphase three-component medium consisting of extracellular matrix, tumor cells, and extracellular fluid. The extracellular matrix is generally deformable. In the case of the predominant extracellular flui...

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Main Authors: Вардан Баландурович Погосян, Маргарита Андреевна Токарева, Александр Алексеевич Папин
Format: Article
Language:English
Published: Altai State University 2024-04-01
Series:Известия Алтайского государственного университета
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Online Access:http://izvestiya.asu.ru/article/view/15015
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author Вардан Баландурович Погосян
Маргарита Андреевна Токарева
Александр Алексеевич Папин
author_facet Вардан Баландурович Погосян
Маргарита Андреевна Токарева
Александр Алексеевич Папин
author_sort Вардан Баландурович Погосян
collection DOAJ
description This article discusses a mathematical model of tumor dynamics. The tissue is considered as a multiphase three-component medium consisting of extracellular matrix, tumor cells, and extracellular fluid. The extracellular matrix is generally deformable. In the case of the predominant extracellular fluid — tumor cell interaction, the original system of equations is reduced to the one parabolic equation degenerating on the solution with a special right-hand side. The property of a finite perturbation propagation velocity for tumor cell saturation is revealed. The introduction describes the essence of the problem. The second part presents the derivation of a mathematical model of tumor dynamics as a three-phase medium. The third part describes a mathematical model for the case when mechanical interaction with extracellular fluid is neglected. The fourth part considers the case of predominant fluid-cell interaction. The fifth part provides a proof of the theorem on the localization of the solution to the equation for the saturation of tumor cell.
format Article
id doaj-art-2c094e81aa3a4af0b7b50fb3c69e7279
institution OA Journals
issn 1561-9443
1561-9451
language English
publishDate 2024-04-01
publisher Altai State University
record_format Article
series Известия Алтайского государственного университета
spelling doaj-art-2c094e81aa3a4af0b7b50fb3c69e72792025-08-20T02:17:52ZengAltai State UniversityИзвестия Алтайского государственного университета1561-94431561-94512024-04-011(135)13814310.14258/izvasu(2024)1-2015015Localization of Solutions to Equations of Tumor DynamicsВардан Баландурович Погосян0Маргарита Андреевна Токарева1Александр Алексеевич Папин2Altai State University, Barnaul, RussiaLavrentyev Institute of Hydrodynamics SB RAS, Novosibirsk, RussiaAltai State University, Barnaul, RussiaThis article discusses a mathematical model of tumor dynamics. The tissue is considered as a multiphase three-component medium consisting of extracellular matrix, tumor cells, and extracellular fluid. The extracellular matrix is generally deformable. In the case of the predominant extracellular fluid — tumor cell interaction, the original system of equations is reduced to the one parabolic equation degenerating on the solution with a special right-hand side. The property of a finite perturbation propagation velocity for tumor cell saturation is revealed. The introduction describes the essence of the problem. The second part presents the derivation of a mathematical model of tumor dynamics as a three-phase medium. The third part describes a mathematical model for the case when mechanical interaction with extracellular fluid is neglected. The fourth part considers the case of predominant fluid-cell interaction. The fifth part provides a proof of the theorem on the localization of the solution to the equation for the saturation of tumor cell.http://izvestiya.asu.ru/article/view/15015differential equationsfiltrationtumorlocalizationporosity
spellingShingle Вардан Баландурович Погосян
Маргарита Андреевна Токарева
Александр Алексеевич Папин
Localization of Solutions to Equations of Tumor Dynamics
Известия Алтайского государственного университета
differential equations
filtration
tumor
localization
porosity
title Localization of Solutions to Equations of Tumor Dynamics
title_full Localization of Solutions to Equations of Tumor Dynamics
title_fullStr Localization of Solutions to Equations of Tumor Dynamics
title_full_unstemmed Localization of Solutions to Equations of Tumor Dynamics
title_short Localization of Solutions to Equations of Tumor Dynamics
title_sort localization of solutions to equations of tumor dynamics
topic differential equations
filtration
tumor
localization
porosity
url http://izvestiya.asu.ru/article/view/15015
work_keys_str_mv AT vardanbalandurovičpogosân localizationofsolutionstoequationsoftumordynamics
AT margaritaandreevnatokareva localizationofsolutionstoequationsoftumordynamics
AT aleksandralekseevičpapin localizationofsolutionstoequationsoftumordynamics