Clinical and pathogenetic substantiation of the use of Wobenzim in the complex treatment of generalized periodontitis.
The purpose of this study was to determine the efficacy of using Wobenzim as a general therapy in the complex treatment of generalized periodontitis. 61 patients, I-II degree of severity, with tooth safety in an amount of at least 90%, without concomitant general pathology requiring treatment for th...
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| Format: | Article |
| Language: | English |
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Dnipro State Medical University
2018-06-01
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| Series: | Medičnì Perspektivi |
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| Online Access: | http://journals.uran.ua/index.php/2307-0404/article/view/133947 |
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| author | I. S. Mashchenko T. O. Kucherenko |
| author_facet | I. S. Mashchenko T. O. Kucherenko |
| author_sort | I. S. Mashchenko |
| collection | DOAJ |
| description | The purpose of this study was to determine the efficacy of using Wobenzim as a general therapy in the complex treatment of generalized periodontitis. 61 patients, I-II degree of severity, with tooth safety in an amount of at least 90%, without concomitant general pathology requiring treatment for the current time were examined. Comparative effectiveness of treatment was studied in 2 groups similar in all clinical indices. The main (31 people) patients, along with the symptomatic treatment received Wobenzim; control (30 people) - polytherapy (immunocorrecting, antioxidant, antimicrobial agents). As a result of the generally accepted clinical, paraclinical, immunological and biochemical studies conducted during the treatment and at long-term follow-up, it was found that the use of systemic enzyme therapy in this category of patients ensures rapid regression of the main clinical symptoms (on days 6-7), elimination of pathogenetic links of the disease more than in 90% of treated patients and the onset of remission for at least 6-12 months. It is characteristic that during the monotherapy with Wobenzim, positive results of treatment of generalized periodontitis were achieved, similar to those with the use of complex standard therapy, including administration of a number of medications with targeted action on pathogenesis mechanisms of the disease. From the position of evidence-based medicine, the expediency of replacing a broad arsenal of medicines in the complex treatment of generalized periodontitis with certain pharmacological preparations with a systemic effect is justified. |
| format | Article |
| id | doaj-art-2bfc84e201c94dc5bd7900e402d305ef |
| institution | DOAJ |
| issn | 2307-0404 |
| language | English |
| publishDate | 2018-06-01 |
| publisher | Dnipro State Medical University |
| record_format | Article |
| series | Medičnì Perspektivi |
| spelling | doaj-art-2bfc84e201c94dc5bd7900e402d305ef2025-08-20T02:43:58ZengDnipro State Medical UniversityMedičnì Perspektivi2307-04042018-06-0123211111910.26641/2307-0404.2018.2.133947133947Clinical and pathogenetic substantiation of the use of Wobenzim in the complex treatment of generalized periodontitis.I. S. MashchenkoT. O. KucherenkoThe purpose of this study was to determine the efficacy of using Wobenzim as a general therapy in the complex treatment of generalized periodontitis. 61 patients, I-II degree of severity, with tooth safety in an amount of at least 90%, without concomitant general pathology requiring treatment for the current time were examined. Comparative effectiveness of treatment was studied in 2 groups similar in all clinical indices. The main (31 people) patients, along with the symptomatic treatment received Wobenzim; control (30 people) - polytherapy (immunocorrecting, antioxidant, antimicrobial agents). As a result of the generally accepted clinical, paraclinical, immunological and biochemical studies conducted during the treatment and at long-term follow-up, it was found that the use of systemic enzyme therapy in this category of patients ensures rapid regression of the main clinical symptoms (on days 6-7), elimination of pathogenetic links of the disease more than in 90% of treated patients and the onset of remission for at least 6-12 months. It is characteristic that during the monotherapy with Wobenzim, positive results of treatment of generalized periodontitis were achieved, similar to those with the use of complex standard therapy, including administration of a number of medications with targeted action on pathogenesis mechanisms of the disease. From the position of evidence-based medicine, the expediency of replacing a broad arsenal of medicines in the complex treatment of generalized periodontitis with certain pharmacological preparations with a systemic effect is justified.http://journals.uran.ua/index.php/2307-0404/article/view/133947generalized periodontitiswobenzymmonotherapy |
| spellingShingle | I. S. Mashchenko T. O. Kucherenko Clinical and pathogenetic substantiation of the use of Wobenzim in the complex treatment of generalized periodontitis. Medičnì Perspektivi generalized periodontitis wobenzym monotherapy |
| title | Clinical and pathogenetic substantiation of the use of Wobenzim in the complex treatment of generalized periodontitis. |
| title_full | Clinical and pathogenetic substantiation of the use of Wobenzim in the complex treatment of generalized periodontitis. |
| title_fullStr | Clinical and pathogenetic substantiation of the use of Wobenzim in the complex treatment of generalized periodontitis. |
| title_full_unstemmed | Clinical and pathogenetic substantiation of the use of Wobenzim in the complex treatment of generalized periodontitis. |
| title_short | Clinical and pathogenetic substantiation of the use of Wobenzim in the complex treatment of generalized periodontitis. |
| title_sort | clinical and pathogenetic substantiation of the use of wobenzim in the complex treatment of generalized periodontitis |
| topic | generalized periodontitis wobenzym monotherapy |
| url | http://journals.uran.ua/index.php/2307-0404/article/view/133947 |
| work_keys_str_mv | AT ismashchenko clinicalandpathogeneticsubstantiationoftheuseofwobenziminthecomplextreatmentofgeneralizedperiodontitis AT tokucherenko clinicalandpathogeneticsubstantiationoftheuseofwobenziminthecomplextreatmentofgeneralizedperiodontitis |