A Case of Oropharyngeal Bullous Pemphigoid Presenting with Haemoptysis
Objective. Bullous pemphigoid is well known for its cutaneous features; however in rare cases it may present with mucosal involvement. We report a case of bullous pemphigoid presenting with haemoptysis, initially presenting to the Ear, Nose and Throat Department for investigation. Methods. An 87-yea...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | Case Reports in Otolaryngology |
| Online Access: | http://dx.doi.org/10.1155/2015/631098 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849387200926449664 |
|---|---|
| author | C. M. Lee H. K. Leadbetter J. M. Fishman |
| author_facet | C. M. Lee H. K. Leadbetter J. M. Fishman |
| author_sort | C. M. Lee |
| collection | DOAJ |
| description | Objective. Bullous pemphigoid is well known for its cutaneous features; however in rare cases it may present with mucosal involvement. We report a case of bullous pemphigoid presenting with haemoptysis, initially presenting to the Ear, Nose and Throat Department for investigation. Methods. An 87-year-old lady was admitted with haemoptysis. She also complained of a spreading, pruritic, bullous rash, which first began three weeks previously. Initial investigations, which included nasendoscopy, revealed a normal nasal mucosa and a normal postnasal space. A large deroofed blister was observed on the soft palate. The presenting symptoms and signs raised the suspicion of an immunobullous disease including bullous pemphigoid. Conclusion. Bullous pemphigoid (BP) is a subepidermal immunobullous disease that typically manifests in elderly patient populations. Although rare, BP can present in a mucocutaneous fashion akin to its more aggressive variant, mucous membrane pemphigoid (MMP). Differentiation of the two is based on clinical grounds, with the prevailing feature for the latter being the predominance of mucosal involvement, which may be extensive. The mainstay of treatment for bullous pemphigoid is steroid therapy, which may be administered both topically and systemically. A deeper understanding into the pathophysiology of the various immunobullous diseases may assist in our understanding of how the various disease entities manifest themselves. |
| format | Article |
| id | doaj-art-2bf8ea1e75b8487cb28cd38005d45acf |
| institution | Kabale University |
| issn | 2090-6765 2090-6773 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Otolaryngology |
| spelling | doaj-art-2bf8ea1e75b8487cb28cd38005d45acf2025-08-20T03:55:17ZengWileyCase Reports in Otolaryngology2090-67652090-67732015-01-01201510.1155/2015/631098631098A Case of Oropharyngeal Bullous Pemphigoid Presenting with HaemoptysisC. M. Lee0H. K. Leadbetter1J. M. Fishman2Department of Dermatology, Royal Berkshire Hospital, London Road, Reading, Berkshire RG1 5AN, UKDepartment of Ear, Nose and Throat Surgery, Royal Berkshire Hospital, Reading RG1 5AN, UKDepartment of Ear, Nose and Throat Surgery, Royal Berkshire Hospital, Reading RG1 5AN, UKObjective. Bullous pemphigoid is well known for its cutaneous features; however in rare cases it may present with mucosal involvement. We report a case of bullous pemphigoid presenting with haemoptysis, initially presenting to the Ear, Nose and Throat Department for investigation. Methods. An 87-year-old lady was admitted with haemoptysis. She also complained of a spreading, pruritic, bullous rash, which first began three weeks previously. Initial investigations, which included nasendoscopy, revealed a normal nasal mucosa and a normal postnasal space. A large deroofed blister was observed on the soft palate. The presenting symptoms and signs raised the suspicion of an immunobullous disease including bullous pemphigoid. Conclusion. Bullous pemphigoid (BP) is a subepidermal immunobullous disease that typically manifests in elderly patient populations. Although rare, BP can present in a mucocutaneous fashion akin to its more aggressive variant, mucous membrane pemphigoid (MMP). Differentiation of the two is based on clinical grounds, with the prevailing feature for the latter being the predominance of mucosal involvement, which may be extensive. The mainstay of treatment for bullous pemphigoid is steroid therapy, which may be administered both topically and systemically. A deeper understanding into the pathophysiology of the various immunobullous diseases may assist in our understanding of how the various disease entities manifest themselves.http://dx.doi.org/10.1155/2015/631098 |
| spellingShingle | C. M. Lee H. K. Leadbetter J. M. Fishman A Case of Oropharyngeal Bullous Pemphigoid Presenting with Haemoptysis Case Reports in Otolaryngology |
| title | A Case of Oropharyngeal Bullous Pemphigoid Presenting with Haemoptysis |
| title_full | A Case of Oropharyngeal Bullous Pemphigoid Presenting with Haemoptysis |
| title_fullStr | A Case of Oropharyngeal Bullous Pemphigoid Presenting with Haemoptysis |
| title_full_unstemmed | A Case of Oropharyngeal Bullous Pemphigoid Presenting with Haemoptysis |
| title_short | A Case of Oropharyngeal Bullous Pemphigoid Presenting with Haemoptysis |
| title_sort | case of oropharyngeal bullous pemphigoid presenting with haemoptysis |
| url | http://dx.doi.org/10.1155/2015/631098 |
| work_keys_str_mv | AT cmlee acaseoforopharyngealbullouspemphigoidpresentingwithhaemoptysis AT hkleadbetter acaseoforopharyngealbullouspemphigoidpresentingwithhaemoptysis AT jmfishman acaseoforopharyngealbullouspemphigoidpresentingwithhaemoptysis AT cmlee caseoforopharyngealbullouspemphigoidpresentingwithhaemoptysis AT hkleadbetter caseoforopharyngealbullouspemphigoidpresentingwithhaemoptysis AT jmfishman caseoforopharyngealbullouspemphigoidpresentingwithhaemoptysis |