Review of Exercise Interventions to Improve Clinical Outcomes in Nondialysis CKD

Exercise interventions in chronic kidney disease (CKD) have received growing interest, with over 30 meta-analyses published in the past 5 years. The potential benefits of exercise training in CKD range from slowing disease progression to improving comorbidities and quality of life. Nevertheless, the...

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Main Authors: Christopher M.T. Hayden, Gwénaëlle Begue, Jorge L. Gamboa, Keith Baar, Baback Roshanravan
Format: Article
Language:English
Published: Elsevier 2024-11-01
Series:Kidney International Reports
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Online Access:http://www.sciencedirect.com/science/article/pii/S246802492401862X
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author Christopher M.T. Hayden
Gwénaëlle Begue
Jorge L. Gamboa
Keith Baar
Baback Roshanravan
author_facet Christopher M.T. Hayden
Gwénaëlle Begue
Jorge L. Gamboa
Keith Baar
Baback Roshanravan
author_sort Christopher M.T. Hayden
collection DOAJ
description Exercise interventions in chronic kidney disease (CKD) have received growing interest, with over 30 meta-analyses published in the past 5 years. The potential benefits of exercise training in CKD range from slowing disease progression to improving comorbidities and quality of life. Nevertheless, there is a lack of large, randomized control trials in diverse populations, particularly regarding exercise in nondialysis-dependent CKD (NDD). When exercise interventions are implemented, they often lack fundamental features of exercise training such as progressive overload, personalization, and specificity. Furthermore, the physiology of exercise and CKD-specific barriers appear poorly understood. This review explores the potential benefits of exercise training in NDD, draws lessons from previous interventions and other fields, and provides several basic tools that may help improve interventions in research and practice.
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spelling doaj-art-2bee4201f3af42ae8de147e963e9071c2025-08-20T03:21:11ZengElsevierKidney International Reports2468-02492024-11-019113097311510.1016/j.ekir.2024.07.032Review of Exercise Interventions to Improve Clinical Outcomes in Nondialysis CKDChristopher M.T. Hayden0Gwénaëlle Begue1Jorge L. Gamboa2Keith Baar3Baback Roshanravan4Department of Neurobiology, Physiology and Behavior, University of California Davis, Davis, California, USAKinesiology Department, California State University, Sacramento, California, USADepartment of Medicine, Division of Clinical Pharmacology. Vanderbilt University. Nashville, Tennessee, USADepartment of Neurobiology, Physiology and Behavior, University of California Davis, Davis, California, USA; Department of Physiology and Membrane Biology, University of California Davis, Davis, California, USADepartment of Medicine, Division of Nephrology. University of California Davis. Sacramento, California, USA; Correspondence: Baback Roshanravan, Department of Medicine, Division of Nephrology, Genome Biomedical Sciences Facility, 451 Health Sciences Dr., Suite 5321, Davis, California 95616, USA.Exercise interventions in chronic kidney disease (CKD) have received growing interest, with over 30 meta-analyses published in the past 5 years. The potential benefits of exercise training in CKD range from slowing disease progression to improving comorbidities and quality of life. Nevertheless, there is a lack of large, randomized control trials in diverse populations, particularly regarding exercise in nondialysis-dependent CKD (NDD). When exercise interventions are implemented, they often lack fundamental features of exercise training such as progressive overload, personalization, and specificity. Furthermore, the physiology of exercise and CKD-specific barriers appear poorly understood. This review explores the potential benefits of exercise training in NDD, draws lessons from previous interventions and other fields, and provides several basic tools that may help improve interventions in research and practice.http://www.sciencedirect.com/science/article/pii/S246802492401862Xaerobic capacityendurance trainingnephrologyrenalresistance training
spellingShingle Christopher M.T. Hayden
Gwénaëlle Begue
Jorge L. Gamboa
Keith Baar
Baback Roshanravan
Review of Exercise Interventions to Improve Clinical Outcomes in Nondialysis CKD
Kidney International Reports
aerobic capacity
endurance training
nephrology
renal
resistance training
title Review of Exercise Interventions to Improve Clinical Outcomes in Nondialysis CKD
title_full Review of Exercise Interventions to Improve Clinical Outcomes in Nondialysis CKD
title_fullStr Review of Exercise Interventions to Improve Clinical Outcomes in Nondialysis CKD
title_full_unstemmed Review of Exercise Interventions to Improve Clinical Outcomes in Nondialysis CKD
title_short Review of Exercise Interventions to Improve Clinical Outcomes in Nondialysis CKD
title_sort review of exercise interventions to improve clinical outcomes in nondialysis ckd
topic aerobic capacity
endurance training
nephrology
renal
resistance training
url http://www.sciencedirect.com/science/article/pii/S246802492401862X
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