Random access and semantic search in DNA data storage enabled by Cas9 and machine-guided design

Random access and semantic search in DNA data storage enabled by Cas9 and machine-guided design

Abstract DNA is a promising medium for digital data storage due to its exceptional data density and longevity. Practical DNA-based storage systems require selective data retrieval to minimize decoding time and costs. In this work, we introduce CRISPR-Cas9 as a user-friendly tool for multiplexed, low...

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Bibliographic Details
Main Authors: Carina Imburgia, Lee Organick, Karen Zhang, Nicolas Cardozo, Jeff McBride, Callista Bee, Delaney Wilde, Gwendolin Roote, Sophia Jorgensen, David Ward, Charlie Anderson, Karin Strauss, Luis Ceze, Jeff Nivala
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61264-5
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