Onychomycosis due to Candida parapsilosis in a Child with Ventricular Septal Defect: An Unusual Predisposition
Candida parapsilosis is emerging as a potential pathogen for onychomycosis. A 4-year-old male child with perimembranous ventricular septal defect (VSD) was admitted with features of cystitis and was treated with broad spectrum antibiotics. Two weeks later, he developed yellowish discoloration of nai...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2016/7026068 |
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| author | Supram Hosuru Subramanya Deependra Hamal Niranjan Nayak Shishir Gokhale |
| author_facet | Supram Hosuru Subramanya Deependra Hamal Niranjan Nayak Shishir Gokhale |
| author_sort | Supram Hosuru Subramanya |
| collection | DOAJ |
| description | Candida parapsilosis is emerging as a potential pathogen for onychomycosis. A 4-year-old male child with perimembranous ventricular septal defect (VSD) was admitted with features of cystitis and was treated with broad spectrum antibiotics. Two weeks later, he developed yellowish discoloration of nails of both hands. The sloughed out nail, on microscopy, showed numerous yeast forms that were identified as Candida parapsilosis by both phenotypic and genotypic methods. Antifungal sensitivity testing of the isolate was performed by microbroth dilution method in accordance with CLSI guidelines. Patient was successfully treated with topical amphotericin B and oral fluconazole. Thus, one should have a high index of suspicion of C. parapsilosis onychomycosis, especially when the patient is in the paediatric age group, presenting with unusual predisposing condition like congenital heart disease, and is on broad spectrum antibiotics. |
| format | Article |
| id | doaj-art-2be5ca8bfbd24f759d386247a892e677 |
| institution | OA Journals |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-2be5ca8bfbd24f759d386247a892e6772025-08-20T02:04:49ZengWileyCase Reports in Pediatrics2090-68032090-68112016-01-01201610.1155/2016/70260687026068Onychomycosis due to Candida parapsilosis in a Child with Ventricular Septal Defect: An Unusual PredispositionSupram Hosuru Subramanya0Deependra Hamal1Niranjan Nayak2Shishir Gokhale3Department of Microbiology, Manipal College of Medical Sciences, Pokhara 33700, NepalDepartment of Microbiology, Manipal College of Medical Sciences, Pokhara 33700, NepalDepartment of Microbiology, Manipal College of Medical Sciences, Pokhara 33700, NepalDepartment of Microbiology, Manipal College of Medical Sciences, Pokhara 33700, NepalCandida parapsilosis is emerging as a potential pathogen for onychomycosis. A 4-year-old male child with perimembranous ventricular septal defect (VSD) was admitted with features of cystitis and was treated with broad spectrum antibiotics. Two weeks later, he developed yellowish discoloration of nails of both hands. The sloughed out nail, on microscopy, showed numerous yeast forms that were identified as Candida parapsilosis by both phenotypic and genotypic methods. Antifungal sensitivity testing of the isolate was performed by microbroth dilution method in accordance with CLSI guidelines. Patient was successfully treated with topical amphotericin B and oral fluconazole. Thus, one should have a high index of suspicion of C. parapsilosis onychomycosis, especially when the patient is in the paediatric age group, presenting with unusual predisposing condition like congenital heart disease, and is on broad spectrum antibiotics.http://dx.doi.org/10.1155/2016/7026068 |
| spellingShingle | Supram Hosuru Subramanya Deependra Hamal Niranjan Nayak Shishir Gokhale Onychomycosis due to Candida parapsilosis in a Child with Ventricular Septal Defect: An Unusual Predisposition Case Reports in Pediatrics |
| title | Onychomycosis due to Candida parapsilosis in a Child with Ventricular Septal Defect: An Unusual Predisposition |
| title_full | Onychomycosis due to Candida parapsilosis in a Child with Ventricular Septal Defect: An Unusual Predisposition |
| title_fullStr | Onychomycosis due to Candida parapsilosis in a Child with Ventricular Septal Defect: An Unusual Predisposition |
| title_full_unstemmed | Onychomycosis due to Candida parapsilosis in a Child with Ventricular Septal Defect: An Unusual Predisposition |
| title_short | Onychomycosis due to Candida parapsilosis in a Child with Ventricular Septal Defect: An Unusual Predisposition |
| title_sort | onychomycosis due to candida parapsilosis in a child with ventricular septal defect an unusual predisposition |
| url | http://dx.doi.org/10.1155/2016/7026068 |
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