Hepatic Angiosarcoma with eosinophilia: A Case Report and Literature Review

Meiqin Chen,1 Xiguo Chen,2 Shun Wang,1 Dan Lei,1 Chunxian Peng1 1Department of Infectious Diseases, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, People’s Hospital, Quzhou, People’s Republic of China; 2Department of Electromechanical Engineering, Quzhou College of Technology,...

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Main Authors: Chen M, Chen X, Wang S, Lei D, Peng C
Format: Article
Language:English
Published: Dove Medical Press 2025-03-01
Series:International Journal of Women's Health
Subjects:
Online Access:https://www.dovepress.com/hepatic-angiosarcoma-with-eosinophilia-a-case-report-and-literature-re-peer-reviewed-fulltext-article-IJWH
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author Chen M
Chen X
Wang S
Lei D
Peng C
author_facet Chen M
Chen X
Wang S
Lei D
Peng C
author_sort Chen M
collection DOAJ
description Meiqin Chen,1 Xiguo Chen,2 Shun Wang,1 Dan Lei,1 Chunxian Peng1 1Department of Infectious Diseases, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, People’s Hospital, Quzhou, People’s Republic of China; 2Department of Electromechanical Engineering, Quzhou College of Technology, Quzhou, People’s Republic of ChinaCorrespondence: Chunxian Peng, Email springpeng1999@163.comBackground: Hepatic angiosarcoma is an extremely rare, uncontrollable tumor with strong invasion, high mortality rate, and extremely poor prognosis. There is first report on hepatic angiosarcoma accompanied by eosinophilia.Case Presentation: A woman with a chief complaint of poor appetite for about 3 months presented to a local hospital with a liver mass. Laboratory examination revealed a significant increase in eosinophils count was 9.58% in the serum. Abdominal MRI revealed multiple focal high-density lesions in the liver and spleen, and cranial MRI revealed multiple high-density shadows in the skull. Laparoscopic biopsy revealed a hepatic angiosarcoma and targeted treatment with Anlotinib was performed. Two months later, the patient died of splenic rupture and bleeding.Conclusion: Hepatic angiosarcoma often has no specific clinical manifestations, and we found that this case can lead to an increase in eosinophils, which is worth the attention of clinical physicians.Keywords: hepatic angiosarcoma, eosinophilia, prognosis, diagnosis, case report
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publishDate 2025-03-01
publisher Dove Medical Press
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series International Journal of Women's Health
spelling doaj-art-2bdd35c2c1ee454c99e1ac107775d3372025-08-20T02:56:13ZengDove Medical PressInternational Journal of Women's Health1179-14112025-03-01Volume 17785791101123Hepatic Angiosarcoma with eosinophilia: A Case Report and Literature ReviewChen MChen XWang SLei DPeng CMeiqin Chen,1 Xiguo Chen,2 Shun Wang,1 Dan Lei,1 Chunxian Peng1 1Department of Infectious Diseases, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou, People’s Hospital, Quzhou, People’s Republic of China; 2Department of Electromechanical Engineering, Quzhou College of Technology, Quzhou, People’s Republic of ChinaCorrespondence: Chunxian Peng, Email springpeng1999@163.comBackground: Hepatic angiosarcoma is an extremely rare, uncontrollable tumor with strong invasion, high mortality rate, and extremely poor prognosis. There is first report on hepatic angiosarcoma accompanied by eosinophilia.Case Presentation: A woman with a chief complaint of poor appetite for about 3 months presented to a local hospital with a liver mass. Laboratory examination revealed a significant increase in eosinophils count was 9.58% in the serum. Abdominal MRI revealed multiple focal high-density lesions in the liver and spleen, and cranial MRI revealed multiple high-density shadows in the skull. Laparoscopic biopsy revealed a hepatic angiosarcoma and targeted treatment with Anlotinib was performed. Two months later, the patient died of splenic rupture and bleeding.Conclusion: Hepatic angiosarcoma often has no specific clinical manifestations, and we found that this case can lead to an increase in eosinophils, which is worth the attention of clinical physicians.Keywords: hepatic angiosarcoma, eosinophilia, prognosis, diagnosis, case reporthttps://www.dovepress.com/hepatic-angiosarcoma-with-eosinophilia-a-case-report-and-literature-re-peer-reviewed-fulltext-article-IJWHhepatic angiosarcoma;eosinophilia;prognosis;diagnosis;case report
spellingShingle Chen M
Chen X
Wang S
Lei D
Peng C
Hepatic Angiosarcoma with eosinophilia: A Case Report and Literature Review
International Journal of Women's Health
hepatic angiosarcoma;eosinophilia;prognosis;diagnosis;case report
title Hepatic Angiosarcoma with eosinophilia: A Case Report and Literature Review
title_full Hepatic Angiosarcoma with eosinophilia: A Case Report and Literature Review
title_fullStr Hepatic Angiosarcoma with eosinophilia: A Case Report and Literature Review
title_full_unstemmed Hepatic Angiosarcoma with eosinophilia: A Case Report and Literature Review
title_short Hepatic Angiosarcoma with eosinophilia: A Case Report and Literature Review
title_sort hepatic angiosarcoma with eosinophilia a case report and literature review
topic hepatic angiosarcoma;eosinophilia;prognosis;diagnosis;case report
url https://www.dovepress.com/hepatic-angiosarcoma-with-eosinophilia-a-case-report-and-literature-re-peer-reviewed-fulltext-article-IJWH
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AT chenx hepaticangiosarcomawitheosinophiliaacasereportandliteraturereview
AT wangs hepaticangiosarcomawitheosinophiliaacasereportandliteraturereview
AT leid hepaticangiosarcomawitheosinophiliaacasereportandliteraturereview
AT pengc hepaticangiosarcomawitheosinophiliaacasereportandliteraturereview