Qiangyang decoction attenuates ischemia/reperfusion-induced cardiomyocyte ferroptosis via ULK1/KEAP1/Nrf2 axis

Qiangyang decoction attenuates ischemia/reperfusion-induced cardiomyocyte ferroptosis via ULK1/KEAP1/Nrf2 axis

Background: Myocardial ischemia-reperfusion (I/R) induced cardiomyocyte death is a major cause of cardiac dysfunction and fibrosis. Ferroptosis of cardiomyocytes has been demonstrated to contribute to I/R induced injury. Qiangyang decoction (QYD) is commonly used in clinical treatment of hypertensio...

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Bibliographic Details
Main Authors: Jing Wang, Wan Cai, Jingxuan Chen, Wenjin Wang, Wentao Fu, Wen Ge, Hao Chi
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Pharmacological Research - Modern Chinese Medicine
Subjects:
Ferroptosis
Qiangyang decoction
KEAP1
Nrf2
ULK1
Online Access:http://www.sciencedirect.com/science/article/pii/S2667142524002021
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