Reno-protective effect of IL-34 inhibition on cisplatin-induced nephrotoxicity in mice.

Reno-protective effect of IL-34 inhibition on cisplatin-induced nephrotoxicity in mice.

<h4>Introduction</h4>Interleukin-34 (IL-34) shares a receptor (cFMS) with colony stimulating factor-1 (CSF-1), and these two ligands mediate macrophage proliferation. However, in contrast to CSF-1, the influence of IL-34 on tubular epithelial cells (TECs) injury remains unclear. We inves...

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Main Authors: Yukihiro Wada, Masayuki Iyoda, Kei Matsumoto, Taihei Suzuki, Shohei Tachibana, Nobuhiro Kanazawa, Hirokazu Honda
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0245340&type=printable
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