A Case Report on the Thyroid and Eye Connection: A Deep Dive into Evaluation and Treatment Strategies
Thyroid-Associated Orbitopathy (TAO), also known as Graves’ ophthalmopathy or Thyroid Eye Disease (TED), is an autoimmune condition often linked to hyperthyroidism, particularly Graves’ disease. It causes inflammation and swelling of the eye muscles and surrounding tissues, leading to symptoms such...
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JCDR Research and Publications Private Limited
2025-06-01
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| author | Iqra Mushtaq Kalibo Jakhalu Tushar Agrawal Gufran Ali Kamdar |
| author_facet | Iqra Mushtaq Kalibo Jakhalu Tushar Agrawal Gufran Ali Kamdar |
| author_sort | Iqra Mushtaq |
| collection | DOAJ |
| description | Thyroid-Associated Orbitopathy (TAO), also known as Graves’ ophthalmopathy or Thyroid Eye Disease (TED), is an autoimmune condition often linked to hyperthyroidism, particularly Graves’ disease. It causes inflammation and swelling of the eye muscles and surrounding tissues, leading to symptoms such as proptosis, diplopia, and discomfort. The condition is six times more prevalent in females as compared to males. Among individuals diagnosed with TAO, about 90% have Graves’ hyperthyroidism, while a smaller percentage may have primary hypothyroidism, Hashimoto’s thyroiditis, or normal thyroid function. These patterns emphasise the importance of recognising thyroid dysfunction in orbitopathy management which includes treating the underlying thyroid dysfunction, using corticosteroids to reduce inflammation, and applying artificial tears for symptomatic relief. Severe cases may require orbital decompression surgery, strabismus correction, or eyelid surgery. Smoking cessation and selenium supplementation are recommended for improved outcomes in mild-to-moderate cases. A case involving a 42-year-old man is presented here with a history of hyperthyroidism who demonstrated signs of proptosis, diplopia, and upper eyelid retraction in both eyes. Clinical evaluations confirmed inflammation in the orbital tissues, which was substantiated by imaging studies, culminating in a diagnosis of TAO. The patient received intravenous corticosteroids for 12 weeks, reporting significant symptom relief afterward. This case underscores the effectiveness of tailored treatment strategies that combine medical and supportive interventions for managing severe active TED. |
| format | Article |
| id | doaj-art-2bbf8f6e805742babfa7dda383a0c26f |
| institution | Kabale University |
| issn | 2249-782X 0973-709X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | JCDR Research and Publications Private Limited |
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| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj-art-2bbf8f6e805742babfa7dda383a0c26f2025-08-20T03:45:41ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2025-06-01196ND01ND0410.7860/JCDR/2025/76431.21125A Case Report on the Thyroid and Eye Connection: A Deep Dive into Evaluation and Treatment StrategiesIqra Mushtaq0Kalibo Jakhalu1Tushar Agrawal2Gufran Ali Kamdar3Professor, Department of Ophthalmology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune, Maharashtra, India.Resident, Department of Ophthalmology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune, Maharashtra, India.Resident, Department of Ophthalmology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune, Maharashtra, India.Resident, Department of Ophthalmology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pimpri, Pune, Maharashtra, India.Thyroid-Associated Orbitopathy (TAO), also known as Graves’ ophthalmopathy or Thyroid Eye Disease (TED), is an autoimmune condition often linked to hyperthyroidism, particularly Graves’ disease. It causes inflammation and swelling of the eye muscles and surrounding tissues, leading to symptoms such as proptosis, diplopia, and discomfort. The condition is six times more prevalent in females as compared to males. Among individuals diagnosed with TAO, about 90% have Graves’ hyperthyroidism, while a smaller percentage may have primary hypothyroidism, Hashimoto’s thyroiditis, or normal thyroid function. These patterns emphasise the importance of recognising thyroid dysfunction in orbitopathy management which includes treating the underlying thyroid dysfunction, using corticosteroids to reduce inflammation, and applying artificial tears for symptomatic relief. Severe cases may require orbital decompression surgery, strabismus correction, or eyelid surgery. Smoking cessation and selenium supplementation are recommended for improved outcomes in mild-to-moderate cases. A case involving a 42-year-old man is presented here with a history of hyperthyroidism who demonstrated signs of proptosis, diplopia, and upper eyelid retraction in both eyes. Clinical evaluations confirmed inflammation in the orbital tissues, which was substantiated by imaging studies, culminating in a diagnosis of TAO. The patient received intravenous corticosteroids for 12 weeks, reporting significant symptom relief afterward. This case underscores the effectiveness of tailored treatment strategies that combine medical and supportive interventions for managing severe active TED.https://jcdr.net/articles/PDF/21125/76431_CE[Ra1]_F(IS)_PF1(Rf_SS)_PFA(IS)_PB(Rf_IS)_PN(IS).pdfclinical activity scoregraves ophthalmopathyhyperthyroidismproptosisthyroid associated orbitopathy |
| spellingShingle | Iqra Mushtaq Kalibo Jakhalu Tushar Agrawal Gufran Ali Kamdar A Case Report on the Thyroid and Eye Connection: A Deep Dive into Evaluation and Treatment Strategies Journal of Clinical and Diagnostic Research clinical activity score graves ophthalmopathy hyperthyroidism proptosis thyroid associated orbitopathy |
| title | A Case Report on the Thyroid and Eye Connection: A Deep Dive into Evaluation and Treatment Strategies |
| title_full | A Case Report on the Thyroid and Eye Connection: A Deep Dive into Evaluation and Treatment Strategies |
| title_fullStr | A Case Report on the Thyroid and Eye Connection: A Deep Dive into Evaluation and Treatment Strategies |
| title_full_unstemmed | A Case Report on the Thyroid and Eye Connection: A Deep Dive into Evaluation and Treatment Strategies |
| title_short | A Case Report on the Thyroid and Eye Connection: A Deep Dive into Evaluation and Treatment Strategies |
| title_sort | case report on the thyroid and eye connection a deep dive into evaluation and treatment strategies |
| topic | clinical activity score graves ophthalmopathy hyperthyroidism proptosis thyroid associated orbitopathy |
| url | https://jcdr.net/articles/PDF/21125/76431_CE[Ra1]_F(IS)_PF1(Rf_SS)_PFA(IS)_PB(Rf_IS)_PN(IS).pdf |
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