Comparative Analysis of Clinical and Ophthalmic Parameters in Diabetic Patients with and without Diabetic Retinopathy
Background: Diabetic retinopathy (DR), a microvascular disorder occurring due to the long-term effects of diabetes mellitus, is a key vision loss factor. This study compares features and risks in diabetics with and without DR, as well as non-diabetic controls, crucial for early detection and treatme...
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International Medical Research and Development Corporation
2025-06-01
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| Series: | International Journal of Biomedicine |
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| Online Access: | http://www.ijbm.org/articles/i58/ijbm_15(2)_oa4.pdf |
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| author | Anita Syla Lokaj Faruk Semiz Ceren Ece Semiz |
| author_facet | Anita Syla Lokaj Faruk Semiz Ceren Ece Semiz |
| author_sort | Anita Syla Lokaj |
| collection | DOAJ |
| description | Background: Diabetic retinopathy (DR), a microvascular disorder occurring due to the long-term effects of diabetes mellitus, is a key vision loss factor. This study compares features and risks in diabetics with and without DR, as well as non-diabetic controls, crucial for early detection and treatment.
Methods: Three groups (diabetic with retinopathy, diabetic without retinopathy, non-diabetic controls), each with 100 participants and balanced gender, were studied. Age, diabetes duration, visual acuity, intraocular pressure, corneal thickness, glycemic levels, and HbA1c were evaluated. Visual acuity was assessed uncorrected and corrected. Intraocular pressure and corneal thickness were measured using optical coherence tomography (OCT) and ultrasonic pachymetry.
Diabetic patients with retinopathy were older, had longer diabetes duration, and lower visual acuity. Intraocular pressure and corneal thickness by OCT varied significantly, but ultrasonic pachymetry did not. Glycemic levels and HbA1c were higher in diabetic groups, peaking in retinopathy patients.
Conclusion: The study identified significant differences in age, diabetes duration, visual acuity, intraocular pressure, corneal thickness, and glycemic control between DR patients, those without DR, and non-diabetic controls. These findings underscore the necessity for targeted therapies and monitoring strategies for diabetic patients, especially those at risk for or suffering from DR. |
| format | Article |
| id | doaj-art-2bbbce4da41948d2a528638c1db6d479 |
| institution | Kabale University |
| issn | 2158-0510 2158-0529 |
| language | English |
| publishDate | 2025-06-01 |
| publisher | International Medical Research and Development Corporation |
| record_format | Article |
| series | International Journal of Biomedicine |
| spelling | doaj-art-2bbbce4da41948d2a528638c1db6d4792025-08-20T03:24:55ZengInternational Medical Research and Development CorporationInternational Journal of Biomedicine2158-05102158-05292025-06-0115229129810.21103/Article15(2)_OA4Comparative Analysis of Clinical and Ophthalmic Parameters in Diabetic Patients with and without Diabetic RetinopathyAnita Syla Lokaj0Faruk Semiz1Ceren Ece Semiz2University Clinical Center of Kosovo, Eye Clinic, Prishtina, KosovoDepartment of Ophthalmology, Eye Hospital, Prishtina, KosovoGazi University of Medicine, Ankara, TurkeyBackground: Diabetic retinopathy (DR), a microvascular disorder occurring due to the long-term effects of diabetes mellitus, is a key vision loss factor. This study compares features and risks in diabetics with and without DR, as well as non-diabetic controls, crucial for early detection and treatment. Methods: Three groups (diabetic with retinopathy, diabetic without retinopathy, non-diabetic controls), each with 100 participants and balanced gender, were studied. Age, diabetes duration, visual acuity, intraocular pressure, corneal thickness, glycemic levels, and HbA1c were evaluated. Visual acuity was assessed uncorrected and corrected. Intraocular pressure and corneal thickness were measured using optical coherence tomography (OCT) and ultrasonic pachymetry. Diabetic patients with retinopathy were older, had longer diabetes duration, and lower visual acuity. Intraocular pressure and corneal thickness by OCT varied significantly, but ultrasonic pachymetry did not. Glycemic levels and HbA1c were higher in diabetic groups, peaking in retinopathy patients. Conclusion: The study identified significant differences in age, diabetes duration, visual acuity, intraocular pressure, corneal thickness, and glycemic control between DR patients, those without DR, and non-diabetic controls. These findings underscore the necessity for targeted therapies and monitoring strategies for diabetic patients, especially those at risk for or suffering from DR.http://www.ijbm.org/articles/i58/ijbm_15(2)_oa4.pdfdiabetic retinopathyintraocular pressurevisual acuitycentral corneal thickness |
| spellingShingle | Anita Syla Lokaj Faruk Semiz Ceren Ece Semiz Comparative Analysis of Clinical and Ophthalmic Parameters in Diabetic Patients with and without Diabetic Retinopathy International Journal of Biomedicine diabetic retinopathy intraocular pressure visual acuity central corneal thickness |
| title | Comparative Analysis of Clinical and Ophthalmic Parameters in Diabetic Patients with and without Diabetic Retinopathy |
| title_full | Comparative Analysis of Clinical and Ophthalmic Parameters in Diabetic Patients with and without Diabetic Retinopathy |
| title_fullStr | Comparative Analysis of Clinical and Ophthalmic Parameters in Diabetic Patients with and without Diabetic Retinopathy |
| title_full_unstemmed | Comparative Analysis of Clinical and Ophthalmic Parameters in Diabetic Patients with and without Diabetic Retinopathy |
| title_short | Comparative Analysis of Clinical and Ophthalmic Parameters in Diabetic Patients with and without Diabetic Retinopathy |
| title_sort | comparative analysis of clinical and ophthalmic parameters in diabetic patients with and without diabetic retinopathy |
| topic | diabetic retinopathy intraocular pressure visual acuity central corneal thickness |
| url | http://www.ijbm.org/articles/i58/ijbm_15(2)_oa4.pdf |
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