Attitudes and acceptance of vaccination against neglected tropical diseases: A multi-country study in Asia

This study aims to explore the willingness of individuals to be vaccinated against NTDs in Asian countries and China. Between June and December 2023, an anonymous cross-sectional survey was carried out in five Asian countries alongside China. Overall, 48.4% indicated being somewhat willing and 29.2%...

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Main Authors: Li Ping Wong, Hai Yen Lee, Haridah Alias, Farhana Nishat Seheli, Abhishek Lachyan, Di Khanh Nguyen, Jamil Ahmed, Zhijian Hu, Yulan Lin
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Human Vaccines & Immunotherapeutics
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Online Access:https://www.tandfonline.com/doi/10.1080/21645515.2025.2471702
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author Li Ping Wong
Hai Yen Lee
Haridah Alias
Farhana Nishat Seheli
Abhishek Lachyan
Di Khanh Nguyen
Jamil Ahmed
Zhijian Hu
Yulan Lin
author_facet Li Ping Wong
Hai Yen Lee
Haridah Alias
Farhana Nishat Seheli
Abhishek Lachyan
Di Khanh Nguyen
Jamil Ahmed
Zhijian Hu
Yulan Lin
author_sort Li Ping Wong
collection DOAJ
description This study aims to explore the willingness of individuals to be vaccinated against NTDs in Asian countries and China. Between June and December 2023, an anonymous cross-sectional survey was carried out in five Asian countries alongside China. Overall, 48.4% indicated being somewhat willing and 29.2% expressing extreme willingness to receive NTDs vaccination. High attitude scores (adjusted odds ratio [aOR] = 1.54, 95% confidence interval (CI): 11.35–1.75) was associated with higher willingness to be vaccinated against NTDs. The odds of accepting the NTDs vaccine increased among individuals without occupational exposure to NTDs (aOR = 1.46, 95% CI: 1.27–1.68). Those residing in very clean environments exhibited heightened odds of willingness (aOR = 2.94, 95% CI: 2.10–4.11), whereas individuals in somewhat dirty environments demonstrated reduced odds of willingness (aOR = 0.74, 95% CI: 0.56–0.98) compared to the baseline group (very dirty local environment). Moreover, a higher score in sanitation facilities also correlated with increased odds of willingness to receive the NTDs vaccine (aOR = 1.41, 95% CI: 1.21–1.64). The study highlighted key strategies for improving NTDs vaccine uptake in Asian countries, including China, such as fostering positive attitudes toward the vaccine and enhancing perception of infection risks.
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spelling doaj-art-2bbafe4efe2c4616bd4ff16aff719aec2025-08-20T03:48:14ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2025-12-0121110.1080/21645515.2025.2471702Attitudes and acceptance of vaccination against neglected tropical diseases: A multi-country study in AsiaLi Ping Wong0Hai Yen Lee1Haridah Alias2Farhana Nishat Seheli3Abhishek Lachyan4Di Khanh Nguyen5Jamil Ahmed6Zhijian Hu7Yulan Lin8Centre for Population Health (CePH), Department of Social and Preventive Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, MalaysiaTropical Infectious Diseases Research and Educational Centre (TIDREC), Universiti Malaya, Kuala Lumpur, MalaysiaCentre for Population Health (CePH), Department of Social and Preventive Medicine, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, MalaysiaTropical Infectious Diseases Research and Educational Centre (TIDREC), Universiti Malaya, Kuala Lumpur, MalaysiaDepartment of Obstetrics & Gynecology, VMMC & Safdarjung Hospital, New Delhi, IndiaDepartment of Academic Affairs and Testing, Dong Nai Technology University, Dong Nai, VietnamDepartment of Community Medicine, Rashid Latif Khan University (RLKU) Medical College, Lahore, PakistanDepartment of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, Fujian, ChinaDepartment of Epidemiology and Health Statistics, School of Public Health, Fujian Medical University, Fuzhou, Fujian, ChinaThis study aims to explore the willingness of individuals to be vaccinated against NTDs in Asian countries and China. Between June and December 2023, an anonymous cross-sectional survey was carried out in five Asian countries alongside China. Overall, 48.4% indicated being somewhat willing and 29.2% expressing extreme willingness to receive NTDs vaccination. High attitude scores (adjusted odds ratio [aOR] = 1.54, 95% confidence interval (CI): 11.35–1.75) was associated with higher willingness to be vaccinated against NTDs. The odds of accepting the NTDs vaccine increased among individuals without occupational exposure to NTDs (aOR = 1.46, 95% CI: 1.27–1.68). Those residing in very clean environments exhibited heightened odds of willingness (aOR = 2.94, 95% CI: 2.10–4.11), whereas individuals in somewhat dirty environments demonstrated reduced odds of willingness (aOR = 0.74, 95% CI: 0.56–0.98) compared to the baseline group (very dirty local environment). Moreover, a higher score in sanitation facilities also correlated with increased odds of willingness to receive the NTDs vaccine (aOR = 1.41, 95% CI: 1.21–1.64). The study highlighted key strategies for improving NTDs vaccine uptake in Asian countries, including China, such as fostering positive attitudes toward the vaccine and enhancing perception of infection risks.https://www.tandfonline.com/doi/10.1080/21645515.2025.2471702Acceptancevaccinationneglected tropical diseasesAsiamulti-countrycross-sectional study
spellingShingle Li Ping Wong
Hai Yen Lee
Haridah Alias
Farhana Nishat Seheli
Abhishek Lachyan
Di Khanh Nguyen
Jamil Ahmed
Zhijian Hu
Yulan Lin
Attitudes and acceptance of vaccination against neglected tropical diseases: A multi-country study in Asia
Human Vaccines & Immunotherapeutics
Acceptance
vaccination
neglected tropical diseases
Asia
multi-country
cross-sectional study
title Attitudes and acceptance of vaccination against neglected tropical diseases: A multi-country study in Asia
title_full Attitudes and acceptance of vaccination against neglected tropical diseases: A multi-country study in Asia
title_fullStr Attitudes and acceptance of vaccination against neglected tropical diseases: A multi-country study in Asia
title_full_unstemmed Attitudes and acceptance of vaccination against neglected tropical diseases: A multi-country study in Asia
title_short Attitudes and acceptance of vaccination against neglected tropical diseases: A multi-country study in Asia
title_sort attitudes and acceptance of vaccination against neglected tropical diseases a multi country study in asia
topic Acceptance
vaccination
neglected tropical diseases
Asia
multi-country
cross-sectional study
url https://www.tandfonline.com/doi/10.1080/21645515.2025.2471702
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