Experimental Model of Blunt Chest Trauma in Rats
The aim of the study was to present our own experimental model of blunt chest trauma in small laboratory animals. Fifteen Wistar albino rats (body weight 290.0-320.0 g) were used in the experiment. An originally designed platform was used to inflict blunt thoracic trauma in the rats. Gross examinati...
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| Format: | Article |
| Language: | English |
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Medical University - Pleven
2014-11-01
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| Series: | Journal of Biomedical & Clinical Research |
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| Online Access: | https://jbcr.arphahub.com/article/34328/download/pdf/ |
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| _version_ | 1849408992686637056 |
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| author | Ivan Novakov Delyan Delev Svitlana Bachurska Dmitrii Staikov |
| author_facet | Ivan Novakov Delyan Delev Svitlana Bachurska Dmitrii Staikov |
| author_sort | Ivan Novakov |
| collection | DOAJ |
| description | The aim of the study was to present our own experimental model of blunt chest trauma in small laboratory animals. Fifteen Wistar albino rats (body weight 290.0-320.0 g) were used in the experiment. An originally designed platform was used to inflict blunt thoracic trauma in the rats. Gross examination and histological evaluation of the heart and lung were performed. It was established that blunt chest trauma caused three thoracic injuries: bilateral lung contusion, myocardial contusion and hemopericardium. These thoracic injuries occurred as a result from direct compression of the chest wall towards the lung and the heart. The severity of lung parenchymal and myocardial pathological findings depended on the energy of blunt chest trauma. The study presents a reproducible small-animal experimental model of blunt chest trauma. The model gives opportunities for further studying different aspects of lung and myocardial contusion. |
| format | Article |
| id | doaj-art-2bba500248fe407d901fcb13f6130a23 |
| institution | Kabale University |
| issn | 1313-9053 |
| language | English |
| publishDate | 2014-11-01 |
| publisher | Medical University - Pleven |
| record_format | Article |
| series | Journal of Biomedical & Clinical Research |
| spelling | doaj-art-2bba500248fe407d901fcb13f6130a232025-08-20T03:35:38ZengMedical University - PlevenJournal of Biomedical & Clinical Research1313-90532014-11-0171151910.1515/jbcr-2015-011934328Experimental Model of Blunt Chest Trauma in RatsIvan NovakovDelyan DelevSvitlana BachurskaDmitrii StaikovThe aim of the study was to present our own experimental model of blunt chest trauma in small laboratory animals. Fifteen Wistar albino rats (body weight 290.0-320.0 g) were used in the experiment. An originally designed platform was used to inflict blunt thoracic trauma in the rats. Gross examination and histological evaluation of the heart and lung were performed. It was established that blunt chest trauma caused three thoracic injuries: bilateral lung contusion, myocardial contusion and hemopericardium. These thoracic injuries occurred as a result from direct compression of the chest wall towards the lung and the heart. The severity of lung parenchymal and myocardial pathological findings depended on the energy of blunt chest trauma. The study presents a reproducible small-animal experimental model of blunt chest trauma. The model gives opportunities for further studying different aspects of lung and myocardial contusion.https://jbcr.arphahub.com/article/34328/download/pdf/blunt chest contusionmyocardial contusionrats |
| spellingShingle | Ivan Novakov Delyan Delev Svitlana Bachurska Dmitrii Staikov Experimental Model of Blunt Chest Trauma in Rats Journal of Biomedical & Clinical Research blunt chest contusion myocardial contusion rats |
| title | Experimental Model of Blunt Chest Trauma in Rats |
| title_full | Experimental Model of Blunt Chest Trauma in Rats |
| title_fullStr | Experimental Model of Blunt Chest Trauma in Rats |
| title_full_unstemmed | Experimental Model of Blunt Chest Trauma in Rats |
| title_short | Experimental Model of Blunt Chest Trauma in Rats |
| title_sort | experimental model of blunt chest trauma in rats |
| topic | blunt chest contusion myocardial contusion rats |
| url | https://jbcr.arphahub.com/article/34328/download/pdf/ |
| work_keys_str_mv | AT ivannovakov experimentalmodelofbluntchesttraumainrats AT delyandelev experimentalmodelofbluntchesttraumainrats AT svitlanabachurska experimentalmodelofbluntchesttraumainrats AT dmitriistaikov experimentalmodelofbluntchesttraumainrats |