Immunogenicity and protective efficacy of a Vero cell culture-derived whole-virus H7N9 vaccine in mice and guinea pigs.

Immunogenicity and protective efficacy of a Vero cell culture-derived whole-virus H7N9 vaccine in mice and guinea pigs.

<h4>Background</h4>A novel avian H7N9 virus with a high case fatality rate in humans emerged in China in 2013. We evaluated the immunogenicity and protective efficacy of a candidate Vero cell culture-derived whole-virus H7N9 vaccine in small animal models.<h4>Methods</h4>Anti...

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Main Authors: Walter Wodal, Michael G Schwendinger, Helga Savidis-Dacho, Brian A Crowe, Christine Hohenadl, Richard Fritz, Peter Brühl, Daniel Portsmouth, Anita Karner-Pichl, Dalida Balta, Leopold Grillberger, Otfried Kistner, P Noel Barrett, M Keith Howard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0113963&type=printable
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