Pesticides and Parkinson’s Disease
Parkinson’s disease (PD), a common neurodegenerative disorder affects approximately 1% of the population over 65. PD is a late-onset progressive motor disease characterized by tremor, rigidity (stiffness), and bradykinesia (slowness of movement). The hallmark of PD is the selective death of dopamine...
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| Format: | Article |
| Language: | English |
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Wiley
2001-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1100/tsw.2001.35 |
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| author | Todd B. Sherer Ranjita Betarbet J. Timothy Greenamyre |
| author_facet | Todd B. Sherer Ranjita Betarbet J. Timothy Greenamyre |
| author_sort | Todd B. Sherer |
| collection | DOAJ |
| description | Parkinson’s disease (PD), a common neurodegenerative disorder affects approximately 1% of the population over 65. PD is a late-onset progressive motor disease characterized by tremor, rigidity (stiffness), and bradykinesia (slowness of movement). The hallmark of PD is the selective death of dopamine-containing neurons in the substantia nigra pars compacta which send their projections to the striatum and the presence of cytoplasmic aggregates called Lewy bodies [1-2]. Most cases of PD are sporadic but rare cases are familial, with earlier onset. The underlying mechanisms and causes of PD still remain unclear. |
| format | Article |
| id | doaj-art-2bb77162694f455f935cdb41fe08ed29 |
| institution | OA Journals |
| issn | 1537-744X |
| language | English |
| publishDate | 2001-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-2bb77162694f455f935cdb41fe08ed292025-08-20T02:04:31ZengWileyThe Scientific World Journal1537-744X2001-01-01120720810.1100/tsw.2001.35Pesticides and Parkinson’s DiseaseTodd B. Sherer0Ranjita Betarbet1J. Timothy Greenamyre2Department of Neurology, Emory University, Atlanta, GA 30322, USADepartment of Neurology, Emory University, Atlanta, GA 30322, USADepartment of Neurology, Emory University, Atlanta, GA 30322, USAParkinson’s disease (PD), a common neurodegenerative disorder affects approximately 1% of the population over 65. PD is a late-onset progressive motor disease characterized by tremor, rigidity (stiffness), and bradykinesia (slowness of movement). The hallmark of PD is the selective death of dopamine-containing neurons in the substantia nigra pars compacta which send their projections to the striatum and the presence of cytoplasmic aggregates called Lewy bodies [1-2]. Most cases of PD are sporadic but rare cases are familial, with earlier onset. The underlying mechanisms and causes of PD still remain unclear.http://dx.doi.org/10.1100/tsw.2001.35 |
| spellingShingle | Todd B. Sherer Ranjita Betarbet J. Timothy Greenamyre Pesticides and Parkinson’s Disease The Scientific World Journal |
| title | Pesticides and Parkinson’s Disease |
| title_full | Pesticides and Parkinson’s Disease |
| title_fullStr | Pesticides and Parkinson’s Disease |
| title_full_unstemmed | Pesticides and Parkinson’s Disease |
| title_short | Pesticides and Parkinson’s Disease |
| title_sort | pesticides and parkinson s disease |
| url | http://dx.doi.org/10.1100/tsw.2001.35 |
| work_keys_str_mv | AT toddbsherer pesticidesandparkinsonsdisease AT ranjitabetarbet pesticidesandparkinsonsdisease AT jtimothygreenamyre pesticidesandparkinsonsdisease |