Pharmacokinetics Guided Personalized Management of Hemophilia Rehabilitation: A Chinese Consensus Based on Modified Delphi
Hemophilia is a collection of hereditary bleeding disorders that are X-linked recessive. Patients often experience recurrent bleeding in joints, leading to a cascade of complications including chronic synovitis, hemophilic arthropathy, muscle atrophy, and joint contractures. These issues are the pri...
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Editorial Office of Journal of Rare Diseases
2025-01-01
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| Series: | 罕见病研究 |
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| Online Access: | https://jrd.chard.org.cn/article/doi/10.12376/j.issn.2097-0501.2025.01.013 |
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| author | Hemophilia Treatment Center Collaborative Network of China |
| author_facet | Hemophilia Treatment Center Collaborative Network of China |
| author_sort | Hemophilia Treatment Center Collaborative Network of China |
| collection | DOAJ |
| description | Hemophilia is a collection of hereditary bleeding disorders that are X-linked recessive. Patients often experience recurrent bleeding in joints, leading to a cascade of complications including chronic synovitis, hemophilic arthropathy, muscle atrophy, and joint contractures. These issues are the primary causes of functional impairment and disabilities in individuals with hemophilia. Rehabilitation focusing on physical function is crucial in the multidisciplinary management of hemophilia. Nineteen experienced consensus experts invited by the Hemophilia Treatment Center Collaborative Network of China participated in the formulation of the Chinese consensus. Utilizing the modified Delphi method, the experts reached a consensus on nine recommendations for the formulation of hemophilia recovery plans, personalized management under the guidance of pharmacokinetics, and postoperative recovery treatment for orthopedic surgery, providing standardized procedures for evaluating and tailoring rehabilitation for hemophilia patients. Additionally, the investigation results of 22 physiotherapists on the risk assessment of various rehabilitation scenarios were further summarized for clinical reference. |
| format | Article |
| id | doaj-art-2bb3ae6c121045b29d2dfe1ced708ca0 |
| institution | OA Journals |
| issn | 2097-0501 |
| language | zho |
| publishDate | 2025-01-01 |
| publisher | Editorial Office of Journal of Rare Diseases |
| record_format | Article |
| series | 罕见病研究 |
| spelling | doaj-art-2bb3ae6c121045b29d2dfe1ced708ca02025-08-20T02:25:03ZzhoEditorial Office of Journal of Rare Diseases罕见病研究2097-05012025-01-01419610510.12376/j.issn.2097-0501.2025.01.013Pharmacokinetics Guided Personalized Management of Hemophilia Rehabilitation: A Chinese Consensus Based on Modified DelphiHemophilia Treatment Center Collaborative Network of China0Department of Rehabilitation Medicine, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, ChinaHemophilia is a collection of hereditary bleeding disorders that are X-linked recessive. Patients often experience recurrent bleeding in joints, leading to a cascade of complications including chronic synovitis, hemophilic arthropathy, muscle atrophy, and joint contractures. These issues are the primary causes of functional impairment and disabilities in individuals with hemophilia. Rehabilitation focusing on physical function is crucial in the multidisciplinary management of hemophilia. Nineteen experienced consensus experts invited by the Hemophilia Treatment Center Collaborative Network of China participated in the formulation of the Chinese consensus. Utilizing the modified Delphi method, the experts reached a consensus on nine recommendations for the formulation of hemophilia recovery plans, personalized management under the guidance of pharmacokinetics, and postoperative recovery treatment for orthopedic surgery, providing standardized procedures for evaluating and tailoring rehabilitation for hemophilia patients. Additionally, the investigation results of 22 physiotherapists on the risk assessment of various rehabilitation scenarios were further summarized for clinical reference.https://jrd.chard.org.cn/article/doi/10.12376/j.issn.2097-0501.2025.01.013hemophiliarehabilitative treatmentpharmacokineticsexpert consensus |
| spellingShingle | Hemophilia Treatment Center Collaborative Network of China Pharmacokinetics Guided Personalized Management of Hemophilia Rehabilitation: A Chinese Consensus Based on Modified Delphi 罕见病研究 hemophilia rehabilitative treatment pharmacokinetics expert consensus |
| title | Pharmacokinetics Guided Personalized Management of Hemophilia Rehabilitation: A Chinese Consensus Based on Modified Delphi |
| title_full | Pharmacokinetics Guided Personalized Management of Hemophilia Rehabilitation: A Chinese Consensus Based on Modified Delphi |
| title_fullStr | Pharmacokinetics Guided Personalized Management of Hemophilia Rehabilitation: A Chinese Consensus Based on Modified Delphi |
| title_full_unstemmed | Pharmacokinetics Guided Personalized Management of Hemophilia Rehabilitation: A Chinese Consensus Based on Modified Delphi |
| title_short | Pharmacokinetics Guided Personalized Management of Hemophilia Rehabilitation: A Chinese Consensus Based on Modified Delphi |
| title_sort | pharmacokinetics guided personalized management of hemophilia rehabilitation a chinese consensus based on modified delphi |
| topic | hemophilia rehabilitative treatment pharmacokinetics expert consensus |
| url | https://jrd.chard.org.cn/article/doi/10.12376/j.issn.2097-0501.2025.01.013 |
| work_keys_str_mv | AT hemophiliatreatmentcentercollaborativenetworkofchina pharmacokineticsguidedpersonalizedmanagementofhemophiliarehabilitationachineseconsensusbasedonmodifieddelphi |