Silica/Protein and Silica/Polysaccharide Interactions and Their Contributions to the Functional Properties of Derived Hybrid Wound Dressing Hydrogels
Multifunctional and biocompatible hydrogels are on the focus of wound healing treatments. Protein and polysaccharides silica hybrids are interesting wound dressing alternatives. The objective of this review is to answer questions such as why silica for wound dressings reinforcement? What are the rol...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | International Journal of Biomaterials |
| Online Access: | http://dx.doi.org/10.1155/2021/6857204 |
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| _version_ | 1849306952627126272 |
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| author | Monica Mesa Natalia Y. Becerra |
| author_facet | Monica Mesa Natalia Y. Becerra |
| author_sort | Monica Mesa |
| collection | DOAJ |
| description | Multifunctional and biocompatible hydrogels are on the focus of wound healing treatments. Protein and polysaccharides silica hybrids are interesting wound dressing alternatives. The objective of this review is to answer questions such as why silica for wound dressings reinforcement? What are the roles and contributions of silane precursors and silica on the functional properties of hydrogel wound dressings? The effects of tailoring the porous, morphological, and chemical characteristics of synthetic silicas on the bioactivity of hybrid wound dressings hydrogels are explored in the first part of the review. This is followed by a commented review of the mechanisms of silica/protein and silica/polysaccharide interactions and their impact on the barrier, scaffold, and delivery matrix functions of the derived hydrogels. Such information has important consequences for wound healing and paves the way to multidisciplinary researches on the production, processing, and biomedical application of this kind of hybrid materials. |
| format | Article |
| id | doaj-art-2bb2beae9b2549459abda2488f8aaaa8 |
| institution | Kabale University |
| issn | 1687-8795 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Biomaterials |
| spelling | doaj-art-2bb2beae9b2549459abda2488f8aaaa82025-08-20T03:54:56ZengWileyInternational Journal of Biomaterials1687-87952021-01-01202110.1155/2021/6857204Silica/Protein and Silica/Polysaccharide Interactions and Their Contributions to the Functional Properties of Derived Hybrid Wound Dressing HydrogelsMonica Mesa0Natalia Y. Becerra1Materials Science GroupTissue Engineering and Cell Therapy GroupMultifunctional and biocompatible hydrogels are on the focus of wound healing treatments. Protein and polysaccharides silica hybrids are interesting wound dressing alternatives. The objective of this review is to answer questions such as why silica for wound dressings reinforcement? What are the roles and contributions of silane precursors and silica on the functional properties of hydrogel wound dressings? The effects of tailoring the porous, morphological, and chemical characteristics of synthetic silicas on the bioactivity of hybrid wound dressings hydrogels are explored in the first part of the review. This is followed by a commented review of the mechanisms of silica/protein and silica/polysaccharide interactions and their impact on the barrier, scaffold, and delivery matrix functions of the derived hydrogels. Such information has important consequences for wound healing and paves the way to multidisciplinary researches on the production, processing, and biomedical application of this kind of hybrid materials.http://dx.doi.org/10.1155/2021/6857204 |
| spellingShingle | Monica Mesa Natalia Y. Becerra Silica/Protein and Silica/Polysaccharide Interactions and Their Contributions to the Functional Properties of Derived Hybrid Wound Dressing Hydrogels International Journal of Biomaterials |
| title | Silica/Protein and Silica/Polysaccharide Interactions and Their Contributions to the Functional Properties of Derived Hybrid Wound Dressing Hydrogels |
| title_full | Silica/Protein and Silica/Polysaccharide Interactions and Their Contributions to the Functional Properties of Derived Hybrid Wound Dressing Hydrogels |
| title_fullStr | Silica/Protein and Silica/Polysaccharide Interactions and Their Contributions to the Functional Properties of Derived Hybrid Wound Dressing Hydrogels |
| title_full_unstemmed | Silica/Protein and Silica/Polysaccharide Interactions and Their Contributions to the Functional Properties of Derived Hybrid Wound Dressing Hydrogels |
| title_short | Silica/Protein and Silica/Polysaccharide Interactions and Their Contributions to the Functional Properties of Derived Hybrid Wound Dressing Hydrogels |
| title_sort | silica protein and silica polysaccharide interactions and their contributions to the functional properties of derived hybrid wound dressing hydrogels |
| url | http://dx.doi.org/10.1155/2021/6857204 |
| work_keys_str_mv | AT monicamesa silicaproteinandsilicapolysaccharideinteractionsandtheircontributionstothefunctionalpropertiesofderivedhybridwounddressinghydrogels AT nataliaybecerra silicaproteinandsilicapolysaccharideinteractionsandtheircontributionstothefunctionalpropertiesofderivedhybridwounddressinghydrogels |