Towards precise synthetic neural codes: high-dimensional stimulation with flexible electrodes
Abstract Neural representations arise from high-dimensional population activity, but current neuromodulation methods lack the precision to write information into the central nervous system at this complexity. In this perspective, we propose high-dimensional stimulation as an approach to better appro...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-07-01
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| Series: | npj Flexible Electronics |
| Online Access: | https://doi.org/10.1038/s41528-025-00447-y |
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| Summary: | Abstract Neural representations arise from high-dimensional population activity, but current neuromodulation methods lack the precision to write information into the central nervous system at this complexity. In this perspective, we propose high-dimensional stimulation as an approach to better approximate natural neural codes for brain-machine interfaces. Key advancements in resolution, coverage, and safety are essential, with flexible microelectrode arrays offering a promising path toward precise synthetic neural codes. |
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| ISSN: | 2397-4621 |