Cost-Effectiveness of a Short Message Service Intervention to Prevent Type 2 Diabetes from Impaired Glucose Tolerance

Aims. To investigate the costs and cost-effectiveness of a short message service (SMS) intervention to prevent the onset of type 2 diabetes mellitus (T2DM) in subjects with impaired glucose tolerance (IGT). Methods. A Markov model was developed to simulate the cost and effectiveness outcomes of the...

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Main Authors: Carlos K. H. Wong, Fang-Fang Jiao, Shing-Chung Siu, Colman S. C. Fung, Daniel Y. T. Fong, Ka-Wai Wong, Esther Y. T. Yu, Yvonne Y. C. Lo, Cindy L. K. Lam
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2016/1219581
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author Carlos K. H. Wong
Fang-Fang Jiao
Shing-Chung Siu
Colman S. C. Fung
Daniel Y. T. Fong
Ka-Wai Wong
Esther Y. T. Yu
Yvonne Y. C. Lo
Cindy L. K. Lam
author_facet Carlos K. H. Wong
Fang-Fang Jiao
Shing-Chung Siu
Colman S. C. Fung
Daniel Y. T. Fong
Ka-Wai Wong
Esther Y. T. Yu
Yvonne Y. C. Lo
Cindy L. K. Lam
author_sort Carlos K. H. Wong
collection DOAJ
description Aims. To investigate the costs and cost-effectiveness of a short message service (SMS) intervention to prevent the onset of type 2 diabetes mellitus (T2DM) in subjects with impaired glucose tolerance (IGT). Methods. A Markov model was developed to simulate the cost and effectiveness outcomes of the SMS intervention and usual clinical practice from the health provider’s perspective. The direct programme costs and the two-year SMS intervention costs were evaluated in subjects with IGT. All costs were expressed in 2011 US dollars. The incremental cost-effectiveness ratio was calculated as cost per T2DM onset prevented, cost per life year gained, and cost per quality adjusted life year (QALY) gained. Results. Within the two-year trial period, the net intervention cost of the SMS group was $42.03 per subject. The SMS intervention managed to reduce 5.05% onset of diabetes, resulting in saving $118.39 per subject over two years. In the lifetime model, the SMS intervention dominated the control by gaining an additional 0.071 QALY and saving $1020.35 per person. The SMS intervention remained dominant in all sensitivity analyses. Conclusions. The SMS intervention for IGT subjects had the superiority of lower monetary cost and a considerable improvement in preventing or delaying the T2DM onset. This trial is registered with ClinicalTrials.gov NCT01556880.
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spelling doaj-art-2b9914fd71f44d03a391eb6d02d1ea472025-08-20T03:54:56ZengWileyJournal of Diabetes Research2314-67452314-67532016-01-01201610.1155/2016/12195811219581Cost-Effectiveness of a Short Message Service Intervention to Prevent Type 2 Diabetes from Impaired Glucose ToleranceCarlos K. H. Wong0Fang-Fang Jiao1Shing-Chung Siu2Colman S. C. Fung3Daniel Y. T. Fong4Ka-Wai Wong5Esther Y. T. Yu6Yvonne Y. C. Lo7Cindy L. K. Lam8Department of Family Medicine and Primary Care, The University of Hong Kong, Ap Lei Chau, Hong KongDepartment of Family Medicine and Primary Care, The University of Hong Kong, Ap Lei Chau, Hong KongDepartment of Medicine and Rehabilitation, Tung Wah Eastern Hospital, Causeway Bay, Hong KongDepartment of Family Medicine and Primary Care, The University of Hong Kong, Ap Lei Chau, Hong KongSchool of Nursing, The University of Hong Kong, Pokfulam, Hong KongDepartment of Medicine and Rehabilitation, Tung Wah Eastern Hospital, Causeway Bay, Hong KongDepartment of Family Medicine and Primary Care, The University of Hong Kong, Ap Lei Chau, Hong KongDepartment of Family Medicine and Primary Care, The University of Hong Kong, Ap Lei Chau, Hong KongDepartment of Family Medicine and Primary Care, The University of Hong Kong, Ap Lei Chau, Hong KongAims. To investigate the costs and cost-effectiveness of a short message service (SMS) intervention to prevent the onset of type 2 diabetes mellitus (T2DM) in subjects with impaired glucose tolerance (IGT). Methods. A Markov model was developed to simulate the cost and effectiveness outcomes of the SMS intervention and usual clinical practice from the health provider’s perspective. The direct programme costs and the two-year SMS intervention costs were evaluated in subjects with IGT. All costs were expressed in 2011 US dollars. The incremental cost-effectiveness ratio was calculated as cost per T2DM onset prevented, cost per life year gained, and cost per quality adjusted life year (QALY) gained. Results. Within the two-year trial period, the net intervention cost of the SMS group was $42.03 per subject. The SMS intervention managed to reduce 5.05% onset of diabetes, resulting in saving $118.39 per subject over two years. In the lifetime model, the SMS intervention dominated the control by gaining an additional 0.071 QALY and saving $1020.35 per person. The SMS intervention remained dominant in all sensitivity analyses. Conclusions. The SMS intervention for IGT subjects had the superiority of lower monetary cost and a considerable improvement in preventing or delaying the T2DM onset. This trial is registered with ClinicalTrials.gov NCT01556880.http://dx.doi.org/10.1155/2016/1219581
spellingShingle Carlos K. H. Wong
Fang-Fang Jiao
Shing-Chung Siu
Colman S. C. Fung
Daniel Y. T. Fong
Ka-Wai Wong
Esther Y. T. Yu
Yvonne Y. C. Lo
Cindy L. K. Lam
Cost-Effectiveness of a Short Message Service Intervention to Prevent Type 2 Diabetes from Impaired Glucose Tolerance
Journal of Diabetes Research
title Cost-Effectiveness of a Short Message Service Intervention to Prevent Type 2 Diabetes from Impaired Glucose Tolerance
title_full Cost-Effectiveness of a Short Message Service Intervention to Prevent Type 2 Diabetes from Impaired Glucose Tolerance
title_fullStr Cost-Effectiveness of a Short Message Service Intervention to Prevent Type 2 Diabetes from Impaired Glucose Tolerance
title_full_unstemmed Cost-Effectiveness of a Short Message Service Intervention to Prevent Type 2 Diabetes from Impaired Glucose Tolerance
title_short Cost-Effectiveness of a Short Message Service Intervention to Prevent Type 2 Diabetes from Impaired Glucose Tolerance
title_sort cost effectiveness of a short message service intervention to prevent type 2 diabetes from impaired glucose tolerance
url http://dx.doi.org/10.1155/2016/1219581
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