Quantitative study of the effect of tissue microstructure on contraction in a computational model of rat left ventricle.

Tissue microstructure, in particular the alignment of myocytes (fibre direction) and their lateral organisation into sheets, is fundamental to cardiac function. We studied the effect of microstructure on contraction in a computational model of rat left ventricular electromechanics. Different fibre m...

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Bibliographic Details
Main Authors: Valentina Carapella, Rafel Bordas, Pras Pathmanathan, Maelene Lohezic, Jurgen E Schneider, Peter Kohl, Kevin Burrage, Vicente Grau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0092792
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