Optical signature of retinal Tau fibrillation

Optical signature of retinal Tau fibrillation

Abstract Fibrillated Tau proteins are believed to be a signature of Alzheimer’s disease (AD) and may be potentially employed as a biosensor for AD early detection. Several studies revealed the presence of Tau accumulation and aggregation in the retina, similar to that observed in the brains of indiv...

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Bibliographic Details
Main Authors: Zita Salajková, Lorenzo Barolo, Paola Baiocco, Barbara Ruzicka, Francesco Mura, Francesco Di Lorenzo, Alberto Boffi, Vincenzo Ricco, Giancarlo Ruocco, Marco Leonetti
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Tau protein
Protein fibrillation monitoring
Alzheimer’s disease
Side-scattering spectroscopy
Online Access:https://doi.org/10.1038/s41598-025-92565-w
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