False memories activate distinct brain regions in females and males
The constructive process of memory is generally successful; however, it can also lead to memory failures such as false memories. Although true memories and false memories rely on some of the same brain regions, these memory types are also mediated by distinct neural substrates. Of relevance, there i...
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Elsevier
2021-12-01
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| Series: | NeuroImage: Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666956021000416 |
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| author | Dylan S. Spets Jessica M. Karanian Scott D. Slotnick |
| author_facet | Dylan S. Spets Jessica M. Karanian Scott D. Slotnick |
| author_sort | Dylan S. Spets |
| collection | DOAJ |
| description | The constructive process of memory is generally successful; however, it can also lead to memory failures such as false memories. Although true memories and false memories rely on some of the same brain regions, these memory types are also mediated by distinct neural substrates. Of relevance, there is a growing body of evidence that there are sex differences in the brain during true memories. However, no studies have investigated whether there are neural sex differences during false memories. In the current fMRI study, across all subjects, false memories produced activity in the precentral sulcus and superior parietal lobule, replicating previous findings. Males produced greater activity than females in the precuneus, posterior cingulate cortex, parietooccipital sulcus, and fusiform gyrus. Females produced greater activity than males in the medial prefrontal cortex, anterior cingulate cortex, paracentral lobule, supramarginal gyrus, lateral sulcus, cingulate sulcus, the putamen, and V1. An interaction analysis revealed a significant interaction between sex and region with a higher magnitude of activity in the hippocampus for males than females and a higher magnitude of activity in V1 for females than males. The current results suggest that false memories are supported by distinct brain regions and cognitive processes in females and males. |
| format | Article |
| id | doaj-art-2b872718f46f429fb57d8efecbbe3a51 |
| institution | DOAJ |
| issn | 2666-9560 |
| language | English |
| publishDate | 2021-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | NeuroImage: Reports |
| spelling | doaj-art-2b872718f46f429fb57d8efecbbe3a512025-08-20T02:56:59ZengElsevierNeuroImage: Reports2666-95602021-12-011410004310.1016/j.ynirp.2021.100043False memories activate distinct brain regions in females and malesDylan S. Spets0Jessica M. Karanian1Scott D. Slotnick2Department of Psychology and Neuroscience, Boston College, USA; Corresponding author. Department of Psychology and Neuroscience, McGuinn Hall, Boston College, Chestnut Hill, MA, 02467, USA.Department of Psychology, Fairfield University, USADepartment of Psychology and Neuroscience, Boston College, USAThe constructive process of memory is generally successful; however, it can also lead to memory failures such as false memories. Although true memories and false memories rely on some of the same brain regions, these memory types are also mediated by distinct neural substrates. Of relevance, there is a growing body of evidence that there are sex differences in the brain during true memories. However, no studies have investigated whether there are neural sex differences during false memories. In the current fMRI study, across all subjects, false memories produced activity in the precentral sulcus and superior parietal lobule, replicating previous findings. Males produced greater activity than females in the precuneus, posterior cingulate cortex, parietooccipital sulcus, and fusiform gyrus. Females produced greater activity than males in the medial prefrontal cortex, anterior cingulate cortex, paracentral lobule, supramarginal gyrus, lateral sulcus, cingulate sulcus, the putamen, and V1. An interaction analysis revealed a significant interaction between sex and region with a higher magnitude of activity in the hippocampus for males than females and a higher magnitude of activity in V1 for females than males. The current results suggest that false memories are supported by distinct brain regions and cognitive processes in females and males.http://www.sciencedirect.com/science/article/pii/S2666956021000416False memorySex differencesfMRIHippocampusV1Language processing cortex |
| spellingShingle | Dylan S. Spets Jessica M. Karanian Scott D. Slotnick False memories activate distinct brain regions in females and males NeuroImage: Reports False memory Sex differences fMRI Hippocampus V1 Language processing cortex |
| title | False memories activate distinct brain regions in females and males |
| title_full | False memories activate distinct brain regions in females and males |
| title_fullStr | False memories activate distinct brain regions in females and males |
| title_full_unstemmed | False memories activate distinct brain regions in females and males |
| title_short | False memories activate distinct brain regions in females and males |
| title_sort | false memories activate distinct brain regions in females and males |
| topic | False memory Sex differences fMRI Hippocampus V1 Language processing cortex |
| url | http://www.sciencedirect.com/science/article/pii/S2666956021000416 |
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