Vancomycin-resistant Enterococcus infections in a hospital in Salvador, Bahia: a descriptive study, 2021-2023

Abstract Objective To address the occurrence of an outbreak of vancomycin-resistant Enterococcus in inpatient units intended for COVID-19 patients in a hospital in Salvador, Brazil, specialized in infectious diseases, which underwent several adaptations with effect from March 2020. Methods This...

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Main Authors: Verônica França Rocha, Matheus Sales Barbosa, Euclimeire da Silva Neves, Valmira de Jesus Santos, Renata Ferreira da Silva Rego, Tiago Lôbo Pessoa, Marcelo Telles Ribeiro, Jessica Lais Almeida dos Santos, Felicidade Mota Pereira, Joice Neves Reis
Format: Article
Language:English
Published: Ministério da Saúde do Brasil 2025-04-01
Series:Epidemiologia e Serviços de Saúde
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Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-96222025000100218&lng=en&tlng=en
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author Verônica França Rocha
Matheus Sales Barbosa
Euclimeire da Silva Neves
Valmira de Jesus Santos
Renata Ferreira da Silva Rego
Tiago Lôbo Pessoa
Marcelo Telles Ribeiro
Jessica Lais Almeida dos Santos
Felicidade Mota Pereira
Joice Neves Reis
author_facet Verônica França Rocha
Matheus Sales Barbosa
Euclimeire da Silva Neves
Valmira de Jesus Santos
Renata Ferreira da Silva Rego
Tiago Lôbo Pessoa
Marcelo Telles Ribeiro
Jessica Lais Almeida dos Santos
Felicidade Mota Pereira
Joice Neves Reis
author_sort Verônica França Rocha
collection DOAJ
description Abstract Objective To address the occurrence of an outbreak of vancomycin-resistant Enterococcus in inpatient units intended for COVID-19 patients in a hospital in Salvador, Brazil, specialized in infectious diseases, which underwent several adaptations with effect from March 2020. Methods This is a descriptive study of patients with positive culture results for vancomycin-resistant Enterococcus between January 2021 and December 2023. The vanA/vanB genotype was defined by real-time polymerase chain reaction, and the clonal profile, by pulsed-field gel electrophoresis. Descriptive analyses were performed and presented as proportions. Results Fifteen Enterococcus spp. infected/colonized patients were identified, of which 7 were E. faecalis, 7 were E. faecium and 1 was E. gallinarum. Two clonal profiles were identified: E. faecalis profile A and E. faecium profile C. The vanA genotype was predominant. Possible cross-contamination of disinfected materials and other dirty materials used for bathing and waste disposal was detected in utility/sluice room sinks. Conclusion The vancomycin-resistant Enterococcus outbreak in the inpatient units was controlled after implementing a unidirectional flow of disinfection of materials in utility/sluice rooms.
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series Epidemiologia e Serviços de Saúde
spelling doaj-art-2b869217c038498e87c8b5627c056f632025-08-20T02:10:41ZengMinistério da Saúde do BrasilEpidemiologia e Serviços de Saúde2237-96222025-04-013410.1590/s2237-96222024v34e20240135.enVancomycin-resistant Enterococcus infections in a hospital in Salvador, Bahia: a descriptive study, 2021-2023Verônica França Rochahttps://orcid.org/0000-0003-3903-6580Matheus Sales Barbosahttps://orcid.org/0009-0004-3865-7523Euclimeire da Silva Neveshttps://orcid.org/0000-0001-5921-719XValmira de Jesus Santoshttps://orcid.org/0009-0005-9827-3035Renata Ferreira da Silva Regohttps://orcid.org/0009-0006-0176-555XTiago Lôbo Pessoahttps://orcid.org/0009-0001-8702-9556Marcelo Telles Ribeirohttps://orcid.org/0000-0003-0626-0244Jessica Lais Almeida dos Santoshttps://orcid.org/0000-0003-3116-6903Felicidade Mota Pereirahttps://orcid.org/0000-0002-6938-161XJoice Neves Reishttps://orcid.org/0000-0001-5273-2658Abstract Objective To address the occurrence of an outbreak of vancomycin-resistant Enterococcus in inpatient units intended for COVID-19 patients in a hospital in Salvador, Brazil, specialized in infectious diseases, which underwent several adaptations with effect from March 2020. Methods This is a descriptive study of patients with positive culture results for vancomycin-resistant Enterococcus between January 2021 and December 2023. The vanA/vanB genotype was defined by real-time polymerase chain reaction, and the clonal profile, by pulsed-field gel electrophoresis. Descriptive analyses were performed and presented as proportions. Results Fifteen Enterococcus spp. infected/colonized patients were identified, of which 7 were E. faecalis, 7 were E. faecium and 1 was E. gallinarum. Two clonal profiles were identified: E. faecalis profile A and E. faecium profile C. The vanA genotype was predominant. Possible cross-contamination of disinfected materials and other dirty materials used for bathing and waste disposal was detected in utility/sluice room sinks. Conclusion The vancomycin-resistant Enterococcus outbreak in the inpatient units was controlled after implementing a unidirectional flow of disinfection of materials in utility/sluice rooms.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-96222025000100218&lng=en&tlng=enEnterococcus faecalisEnterococcus faeciumVancomycin ResistanceCross InfectionDisease Outbreaks
spellingShingle Verônica França Rocha
Matheus Sales Barbosa
Euclimeire da Silva Neves
Valmira de Jesus Santos
Renata Ferreira da Silva Rego
Tiago Lôbo Pessoa
Marcelo Telles Ribeiro
Jessica Lais Almeida dos Santos
Felicidade Mota Pereira
Joice Neves Reis
Vancomycin-resistant Enterococcus infections in a hospital in Salvador, Bahia: a descriptive study, 2021-2023
Epidemiologia e Serviços de Saúde
Enterococcus faecalis
Enterococcus faecium
Vancomycin Resistance
Cross Infection
Disease Outbreaks
title Vancomycin-resistant Enterococcus infections in a hospital in Salvador, Bahia: a descriptive study, 2021-2023
title_full Vancomycin-resistant Enterococcus infections in a hospital in Salvador, Bahia: a descriptive study, 2021-2023
title_fullStr Vancomycin-resistant Enterococcus infections in a hospital in Salvador, Bahia: a descriptive study, 2021-2023
title_full_unstemmed Vancomycin-resistant Enterococcus infections in a hospital in Salvador, Bahia: a descriptive study, 2021-2023
title_short Vancomycin-resistant Enterococcus infections in a hospital in Salvador, Bahia: a descriptive study, 2021-2023
title_sort vancomycin resistant enterococcus infections in a hospital in salvador bahia a descriptive study 2021 2023
topic Enterococcus faecalis
Enterococcus faecium
Vancomycin Resistance
Cross Infection
Disease Outbreaks
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S2237-96222025000100218&lng=en&tlng=en
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