Depression in Multiple Sclerosis: Lifestyle Interventions as an Additional Therapeutical Approach: A Narrative Review

Depression is one of the most common comorbidities in people with multiple sclerosis, which reduces the quality of life and treatment adherence. It enhances the risk of disease relapse. After looking through the literature, we summarized the newest recommendations that might be helpful in reducing d...

Full description

Saved in:
Bibliographic Details
Main Authors: Matea Hudolin, Hrvoje Budinčević, Dunja Degmečić, Vida Demarin
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Psychiatry International
Subjects:
Online Access:https://www.mdpi.com/2673-5318/6/1/34
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850279992321114112
author Matea Hudolin
Hrvoje Budinčević
Dunja Degmečić
Vida Demarin
author_facet Matea Hudolin
Hrvoje Budinčević
Dunja Degmečić
Vida Demarin
author_sort Matea Hudolin
collection DOAJ
description Depression is one of the most common comorbidities in people with multiple sclerosis, which reduces the quality of life and treatment adherence. It enhances the risk of disease relapse. After looking through the literature, we summarized the newest recommendations that might be helpful in reducing depression severity by reviewing publications regarding depression and multiple sclerosis published in the last five years. Physical activity and rehabilitation should be recommended. The ketogenic diet showed promising results, yet there are possible health concerns that might evolve after a longer period and should only be carried out under medical supervision. Mindfulness and cognitive and dialectical behavior therapy reduce depression severity and can be recommended to depressive people with multiple sclerosis.
format Article
id doaj-art-2b7970cd1bfa44d08ebc65853406ae27
institution OA Journals
issn 2673-5318
language English
publishDate 2025-03-01
publisher MDPI AG
record_format Article
series Psychiatry International
spelling doaj-art-2b7970cd1bfa44d08ebc65853406ae272025-08-20T01:48:54ZengMDPI AGPsychiatry International2673-53182025-03-01613410.3390/psychiatryint6010034Depression in Multiple Sclerosis: Lifestyle Interventions as an Additional Therapeutical Approach: A Narrative ReviewMatea Hudolin0Hrvoje Budinčević1Dunja Degmečić2Vida Demarin3Faculty of Medicine Osijek, J. J. Strossmayer University of Osijek, 31000 Osijek, CroatiaFaculty of Medicine Osijek, J. J. Strossmayer University of Osijek, 31000 Osijek, CroatiaFaculty of Medicine Osijek, J. J. Strossmayer University of Osijek, 31000 Osijek, CroatiaInternational Institute for Brain Health, 10000 Zagreb, CroatiaDepression is one of the most common comorbidities in people with multiple sclerosis, which reduces the quality of life and treatment adherence. It enhances the risk of disease relapse. After looking through the literature, we summarized the newest recommendations that might be helpful in reducing depression severity by reviewing publications regarding depression and multiple sclerosis published in the last five years. Physical activity and rehabilitation should be recommended. The ketogenic diet showed promising results, yet there are possible health concerns that might evolve after a longer period and should only be carried out under medical supervision. Mindfulness and cognitive and dialectical behavior therapy reduce depression severity and can be recommended to depressive people with multiple sclerosis.https://www.mdpi.com/2673-5318/6/1/34multiple sclerosisdepressiontherapy
spellingShingle Matea Hudolin
Hrvoje Budinčević
Dunja Degmečić
Vida Demarin
Depression in Multiple Sclerosis: Lifestyle Interventions as an Additional Therapeutical Approach: A Narrative Review
Psychiatry International
multiple sclerosis
depression
therapy
title Depression in Multiple Sclerosis: Lifestyle Interventions as an Additional Therapeutical Approach: A Narrative Review
title_full Depression in Multiple Sclerosis: Lifestyle Interventions as an Additional Therapeutical Approach: A Narrative Review
title_fullStr Depression in Multiple Sclerosis: Lifestyle Interventions as an Additional Therapeutical Approach: A Narrative Review
title_full_unstemmed Depression in Multiple Sclerosis: Lifestyle Interventions as an Additional Therapeutical Approach: A Narrative Review
title_short Depression in Multiple Sclerosis: Lifestyle Interventions as an Additional Therapeutical Approach: A Narrative Review
title_sort depression in multiple sclerosis lifestyle interventions as an additional therapeutical approach a narrative review
topic multiple sclerosis
depression
therapy
url https://www.mdpi.com/2673-5318/6/1/34
work_keys_str_mv AT mateahudolin depressioninmultiplesclerosislifestyleinterventionsasanadditionaltherapeuticalapproachanarrativereview
AT hrvojebudincevic depressioninmultiplesclerosislifestyleinterventionsasanadditionaltherapeuticalapproachanarrativereview
AT dunjadegmecic depressioninmultiplesclerosislifestyleinterventionsasanadditionaltherapeuticalapproachanarrativereview
AT vidademarin depressioninmultiplesclerosislifestyleinterventionsasanadditionaltherapeuticalapproachanarrativereview