A cryptic plastid and a novel mitochondrial plasmid in Leucomyxa plasmidifera gen. and sp. nov. (Ochrophyta) push the frontiers of organellar biology

Complete plastid loss seems to be very rare among secondarily non-photosynthetic eukaryotes. Leukarachnion sp. PRA-24, an amoeboid colourless protist related to the photosynthetic algal class Synchromophyceae (Ochrophyta), is a candidate for such a case based on a previous investigation by transmiss...

Full description

Saved in:
Bibliographic Details
Main Authors: Dovilė Barcytė, Karin Jaške, Tomáš Pánek, Tatiana Yurchenko, Tereza Ševčíková, Anežka Eliášová, Marek Eliáš
Format: Article
Language:English
Published: The Royal Society 2024-10-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.240022
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850285049031688192
author Dovilė Barcytė
Karin Jaške
Tomáš Pánek
Tatiana Yurchenko
Tereza Ševčíková
Anežka Eliášová
Marek Eliáš
author_facet Dovilė Barcytė
Karin Jaške
Tomáš Pánek
Tatiana Yurchenko
Tereza Ševčíková
Anežka Eliášová
Marek Eliáš
author_sort Dovilė Barcytė
collection DOAJ
description Complete plastid loss seems to be very rare among secondarily non-photosynthetic eukaryotes. Leukarachnion sp. PRA-24, an amoeboid colourless protist related to the photosynthetic algal class Synchromophyceae (Ochrophyta), is a candidate for such a case based on a previous investigation by transmission electron microscopy. Here, we characterize this organism in further detail and describe it as Leucomyxa plasmidifera gen. et sp. nov., additionally demonstrating it is the first known representative of a broader clade of non-photosynthetic ochrophytes. We recovered its complete plastid genome, exhibiting a reduced gene set similar to plastomes of other non-photosynthetic ochrophytes, yet being even more extreme in sequence divergence. Identification of components of the plastid protein import machinery in the L. plasmidifera transcriptome assembly corroborated that the organism possesses a cryptic plastid organelle. According to our bioinformatic reconstruction, the plastid contains a unique combination of biosynthetic pathways producing haem, a folate precursor and tocotrienols. As another twist to its organellar biology, L. plasmidifera turned out to contain an unusual long insertion in its mitogenome related to a newly discovered mitochondrial plasmid exhibiting unprecedented features in terms of its size and coding capacity. Combined, our work uncovered further striking outcomes of the evolutionary course of semiautonomous organelles in protists.
format Article
id doaj-art-2b76109e66e94ba1b45efdc07c9d7a4c
institution OA Journals
issn 2046-2441
language English
publishDate 2024-10-01
publisher The Royal Society
record_format Article
series Open Biology
spelling doaj-art-2b76109e66e94ba1b45efdc07c9d7a4c2025-08-20T01:47:25ZengThe Royal SocietyOpen Biology2046-24412024-10-01141010.1098/rsob.240022A cryptic plastid and a novel mitochondrial plasmid in Leucomyxa plasmidifera gen. and sp. nov. (Ochrophyta) push the frontiers of organellar biologyDovilė Barcytė0Karin Jaške1Tomáš Pánek2Tatiana Yurchenko3Tereza Ševčíková4Anežka Eliášová5Marek Eliáš6Department of Biology and Ecology, Faculty of Science, University of Ostrava, Chittussiho 10 , Ostrava 710 00, Czech RepublicDepartment of Biology and Ecology, Faculty of Science, University of Ostrava, Chittussiho 10 , Ostrava 710 00, Czech RepublicDepartment of Biology and Ecology, Faculty of Science, University of Ostrava, Chittussiho 10 , Ostrava 710 00, Czech RepublicDepartment of Biology and Ecology, Faculty of Science, University of Ostrava, Chittussiho 10 , Ostrava 710 00, Czech RepublicDepartment of Biology and Ecology, Faculty of Science, University of Ostrava, Chittussiho 10 , Ostrava 710 00, Czech RepublicDepartment of Biology and Ecology, Faculty of Science, University of Ostrava, Chittussiho 10 , Ostrava 710 00, Czech RepublicDepartment of Biology and Ecology, Faculty of Science, University of Ostrava, Chittussiho 10 , Ostrava 710 00, Czech RepublicComplete plastid loss seems to be very rare among secondarily non-photosynthetic eukaryotes. Leukarachnion sp. PRA-24, an amoeboid colourless protist related to the photosynthetic algal class Synchromophyceae (Ochrophyta), is a candidate for such a case based on a previous investigation by transmission electron microscopy. Here, we characterize this organism in further detail and describe it as Leucomyxa plasmidifera gen. et sp. nov., additionally demonstrating it is the first known representative of a broader clade of non-photosynthetic ochrophytes. We recovered its complete plastid genome, exhibiting a reduced gene set similar to plastomes of other non-photosynthetic ochrophytes, yet being even more extreme in sequence divergence. Identification of components of the plastid protein import machinery in the L. plasmidifera transcriptome assembly corroborated that the organism possesses a cryptic plastid organelle. According to our bioinformatic reconstruction, the plastid contains a unique combination of biosynthetic pathways producing haem, a folate precursor and tocotrienols. As another twist to its organellar biology, L. plasmidifera turned out to contain an unusual long insertion in its mitogenome related to a newly discovered mitochondrial plasmid exhibiting unprecedented features in terms of its size and coding capacity. Combined, our work uncovered further striking outcomes of the evolutionary course of semiautonomous organelles in protists.https://royalsocietypublishing.org/doi/10.1098/rsob.240022Leukarachnionmitochondrial plasmidsnon-photosynthetic plastidplastid evolutionplastid genomestramenopiles
spellingShingle Dovilė Barcytė
Karin Jaške
Tomáš Pánek
Tatiana Yurchenko
Tereza Ševčíková
Anežka Eliášová
Marek Eliáš
A cryptic plastid and a novel mitochondrial plasmid in Leucomyxa plasmidifera gen. and sp. nov. (Ochrophyta) push the frontiers of organellar biology
Open Biology
Leukarachnion
mitochondrial plasmids
non-photosynthetic plastid
plastid evolution
plastid genome
stramenopiles
title A cryptic plastid and a novel mitochondrial plasmid in Leucomyxa plasmidifera gen. and sp. nov. (Ochrophyta) push the frontiers of organellar biology
title_full A cryptic plastid and a novel mitochondrial plasmid in Leucomyxa plasmidifera gen. and sp. nov. (Ochrophyta) push the frontiers of organellar biology
title_fullStr A cryptic plastid and a novel mitochondrial plasmid in Leucomyxa plasmidifera gen. and sp. nov. (Ochrophyta) push the frontiers of organellar biology
title_full_unstemmed A cryptic plastid and a novel mitochondrial plasmid in Leucomyxa plasmidifera gen. and sp. nov. (Ochrophyta) push the frontiers of organellar biology
title_short A cryptic plastid and a novel mitochondrial plasmid in Leucomyxa plasmidifera gen. and sp. nov. (Ochrophyta) push the frontiers of organellar biology
title_sort cryptic plastid and a novel mitochondrial plasmid in leucomyxa plasmidifera gen and sp nov ochrophyta push the frontiers of organellar biology
topic Leukarachnion
mitochondrial plasmids
non-photosynthetic plastid
plastid evolution
plastid genome
stramenopiles
url https://royalsocietypublishing.org/doi/10.1098/rsob.240022
work_keys_str_mv AT dovilebarcyte acrypticplastidandanovelmitochondrialplasmidinleucomyxaplasmidiferagenandspnovochrophytapushthefrontiersoforganellarbiology
AT karinjaske acrypticplastidandanovelmitochondrialplasmidinleucomyxaplasmidiferagenandspnovochrophytapushthefrontiersoforganellarbiology
AT tomaspanek acrypticplastidandanovelmitochondrialplasmidinleucomyxaplasmidiferagenandspnovochrophytapushthefrontiersoforganellarbiology
AT tatianayurchenko acrypticplastidandanovelmitochondrialplasmidinleucomyxaplasmidiferagenandspnovochrophytapushthefrontiersoforganellarbiology
AT terezasevcikova acrypticplastidandanovelmitochondrialplasmidinleucomyxaplasmidiferagenandspnovochrophytapushthefrontiersoforganellarbiology
AT anezkaeliasova acrypticplastidandanovelmitochondrialplasmidinleucomyxaplasmidiferagenandspnovochrophytapushthefrontiersoforganellarbiology
AT marekelias acrypticplastidandanovelmitochondrialplasmidinleucomyxaplasmidiferagenandspnovochrophytapushthefrontiersoforganellarbiology
AT dovilebarcyte crypticplastidandanovelmitochondrialplasmidinleucomyxaplasmidiferagenandspnovochrophytapushthefrontiersoforganellarbiology
AT karinjaske crypticplastidandanovelmitochondrialplasmidinleucomyxaplasmidiferagenandspnovochrophytapushthefrontiersoforganellarbiology
AT tomaspanek crypticplastidandanovelmitochondrialplasmidinleucomyxaplasmidiferagenandspnovochrophytapushthefrontiersoforganellarbiology
AT tatianayurchenko crypticplastidandanovelmitochondrialplasmidinleucomyxaplasmidiferagenandspnovochrophytapushthefrontiersoforganellarbiology
AT terezasevcikova crypticplastidandanovelmitochondrialplasmidinleucomyxaplasmidiferagenandspnovochrophytapushthefrontiersoforganellarbiology
AT anezkaeliasova crypticplastidandanovelmitochondrialplasmidinleucomyxaplasmidiferagenandspnovochrophytapushthefrontiersoforganellarbiology
AT marekelias crypticplastidandanovelmitochondrialplasmidinleucomyxaplasmidiferagenandspnovochrophytapushthefrontiersoforganellarbiology