Pulmonary metastasectomy for esophageal basaloid squamous cell carcinoma component at 66 months after esophagectomy

Abstract Background Solitary pulmonary metastasis from esophageal basaloid squamous cell carcinoma (BSCC) components is an extremely rare recurrence of esophageal squamous cell carcinoma (SCC). Case presentation A 68-year-old Japanese woman was found to have a suspected malignant mass, approximately...

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Main Authors: Kumiko Sekiguchi, Takeshi Matsutani, Tsutomu Nomura, Nobutoshi Hagiwara, Akihisa Matsuda, Hidetsugu Hanawa, Keisuke Mishima, Nobuhiko Taniai, Ryuji Ohashi, Hiroshi Yoshida
Format: Article
Language:English
Published: Japan Surgical Society 2020-08-01
Series:Surgical Case Reports
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Online Access:http://link.springer.com/article/10.1186/s40792-020-00957-z
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author Kumiko Sekiguchi
Takeshi Matsutani
Tsutomu Nomura
Nobutoshi Hagiwara
Akihisa Matsuda
Hidetsugu Hanawa
Keisuke Mishima
Nobuhiko Taniai
Ryuji Ohashi
Hiroshi Yoshida
author_facet Kumiko Sekiguchi
Takeshi Matsutani
Tsutomu Nomura
Nobutoshi Hagiwara
Akihisa Matsuda
Hidetsugu Hanawa
Keisuke Mishima
Nobuhiko Taniai
Ryuji Ohashi
Hiroshi Yoshida
author_sort Kumiko Sekiguchi
collection DOAJ
description Abstract Background Solitary pulmonary metastasis from esophageal basaloid squamous cell carcinoma (BSCC) components is an extremely rare recurrence of esophageal squamous cell carcinoma (SCC). Case presentation A 68-year-old Japanese woman was found to have a suspected malignant mass, approximately 2 cm in diameter, in her left lower pulmonary lobe, at 66 months after undergoing a curative esophagectomy with three-field lymph node dissection for esophageal SCC with a focal basaloid component. After a CT-guided biopsy, pathological examination indicated a metastasis from esophageal BSCC components. She underwent a thoracoscopic partial resection of the left lower pulmonary lobe for the solitary pulmonary metastasis. The pathohistology of the resected specimen led to diagnosis of metastatic esophageal BSCC, which showed immunohistochemical findings similar to those of the primary esophageal carcinoma. The patient received two courses of adjuvant chemotherapy (5-fluorouracil, docetaxel plus nedaplatin) and recovered to resume a normal life with maintenance therapy. However, multiple lung and brain metastases were diagnosed at 2 years after the pulmonary metastasectomy. She survived 5 years and 6 months after the pulmonary metastasectomy, but died at 10 years and 6 months after her initial esophagectomy. Conclusion This was a rare surgical resected case of solitary pulmonary metastasis from esophageal BSCC components.
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spelling doaj-art-2b75da6d92b34e90bbc3471cdcc2f7b42025-08-20T03:15:08ZengJapan Surgical SocietySurgical Case Reports2198-77932020-08-01611610.1186/s40792-020-00957-zPulmonary metastasectomy for esophageal basaloid squamous cell carcinoma component at 66 months after esophagectomyKumiko Sekiguchi0Takeshi Matsutani1Tsutomu Nomura2Nobutoshi Hagiwara3Akihisa Matsuda4Hidetsugu Hanawa5Keisuke Mishima6Nobuhiko Taniai7Ryuji Ohashi8Hiroshi Yoshida9Department of Gastrointestinal Hepato-Biliary-Pancreatic Surgery, Nippon Medical SchoolDepartment of Gastrointestinal Hepato-Biliary-Pancreatic Surgery, Nippon Medical SchoolDepartment of Gastrointestinal Hepato-Biliary-Pancreatic Surgery, Nippon Medical SchoolDepartment of Gastrointestinal Hepato-Biliary-Pancreatic Surgery, Nippon Medical SchoolDepartment of Gastrointestinal Hepato-Biliary-Pancreatic Surgery, Nippon Medical SchoolDepartment of Digestive Surgery, Nippon Medical School Musashikosugi HospitalDepartment of Digestive Surgery, Nippon Medical School Musashikosugi HospitalDepartment of Digestive Surgery, Nippon Medical School Musashikosugi HospitalDepartment of Integrated Diagnostic Pathology, Nippon Medical SchoolDepartment of Gastrointestinal Hepato-Biliary-Pancreatic Surgery, Nippon Medical SchoolAbstract Background Solitary pulmonary metastasis from esophageal basaloid squamous cell carcinoma (BSCC) components is an extremely rare recurrence of esophageal squamous cell carcinoma (SCC). Case presentation A 68-year-old Japanese woman was found to have a suspected malignant mass, approximately 2 cm in diameter, in her left lower pulmonary lobe, at 66 months after undergoing a curative esophagectomy with three-field lymph node dissection for esophageal SCC with a focal basaloid component. After a CT-guided biopsy, pathological examination indicated a metastasis from esophageal BSCC components. She underwent a thoracoscopic partial resection of the left lower pulmonary lobe for the solitary pulmonary metastasis. The pathohistology of the resected specimen led to diagnosis of metastatic esophageal BSCC, which showed immunohistochemical findings similar to those of the primary esophageal carcinoma. The patient received two courses of adjuvant chemotherapy (5-fluorouracil, docetaxel plus nedaplatin) and recovered to resume a normal life with maintenance therapy. However, multiple lung and brain metastases were diagnosed at 2 years after the pulmonary metastasectomy. She survived 5 years and 6 months after the pulmonary metastasectomy, but died at 10 years and 6 months after her initial esophagectomy. Conclusion This was a rare surgical resected case of solitary pulmonary metastasis from esophageal BSCC components.http://link.springer.com/article/10.1186/s40792-020-00957-zEsophageal basaloid squamous cell carcinomaLung metastasisPulmonary resection
spellingShingle Kumiko Sekiguchi
Takeshi Matsutani
Tsutomu Nomura
Nobutoshi Hagiwara
Akihisa Matsuda
Hidetsugu Hanawa
Keisuke Mishima
Nobuhiko Taniai
Ryuji Ohashi
Hiroshi Yoshida
Pulmonary metastasectomy for esophageal basaloid squamous cell carcinoma component at 66 months after esophagectomy
Surgical Case Reports
Esophageal basaloid squamous cell carcinoma
Lung metastasis
Pulmonary resection
title Pulmonary metastasectomy for esophageal basaloid squamous cell carcinoma component at 66 months after esophagectomy
title_full Pulmonary metastasectomy for esophageal basaloid squamous cell carcinoma component at 66 months after esophagectomy
title_fullStr Pulmonary metastasectomy for esophageal basaloid squamous cell carcinoma component at 66 months after esophagectomy
title_full_unstemmed Pulmonary metastasectomy for esophageal basaloid squamous cell carcinoma component at 66 months after esophagectomy
title_short Pulmonary metastasectomy for esophageal basaloid squamous cell carcinoma component at 66 months after esophagectomy
title_sort pulmonary metastasectomy for esophageal basaloid squamous cell carcinoma component at 66 months after esophagectomy
topic Esophageal basaloid squamous cell carcinoma
Lung metastasis
Pulmonary resection
url http://link.springer.com/article/10.1186/s40792-020-00957-z
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