Reconstitution of T cell‐mediated immunity by umbilical cord‐derived mesenchymal stem cells in ulcerative colitis

Reconstitution of T cell‐mediated immunity by umbilical cord‐derived mesenchymal stem cells in ulcerative colitis

Abstract Background Ulcerative colitis (UC) is an agnogenic chronic intestinal inflammatory disease. Umbilical cord‐derived mesenchymal stem cell (UMSC) is a potential therapeutic approach against UC; however, the mechanisms underlying their efficacy for UC remain unclear. Methods We performed a sin...

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Main Authors: Xiaoying Luo, Jieping Deng, Xiaoke Jiang, Jun Mi, Yangqiu Bai, Huimin Zhang, Yalong Li, Min Liu, Conghui Cai, Pengju Li, Huanrong Huang, Yueping Xu, Yiwen Qin, Yang Mi, Hui Ding, Zhiyu Yang, Yue Wu, Zhenjuan Li, Ling Lan, Lida Zhang, Li Wang, Guobing Chen, Han Yue, Oscar Junhong Luo, Bingyong Zhang
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Clinical and Translational Medicine
Subjects:
immune regulation
single‐cell RNA sequencing
T lymphocyte
ulcerative colitis
umbilical cord‐derived mesenchymal stem cell
Online Access:https://doi.org/10.1002/ctm2.70452
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https://doi.org/10.1002/ctm2.70452

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