Association between TyG-BMI and BPH in a national prospective cohort study
Abstract This study aims to explore the relationship between the Triglyceride Glucose Body Mass Index (TyG-BMI) and the risk of developing benign prostatic hyperplasia (BPH). Utilizing data from the China Health and Retirement Longitudinal Study (CHARLS), we included 3301 men aged 45 and above. We a...
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| Language: | English |
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Nature Portfolio
2025-03-01
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| Series: | Scientific Reports |
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| Online Access: | https://doi.org/10.1038/s41598-024-81629-y |
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| author | Bing Li Zhiqiang Zhang Chao Sun Yaodong Sun Junping Li Xiaoqiang Liu |
| author_facet | Bing Li Zhiqiang Zhang Chao Sun Yaodong Sun Junping Li Xiaoqiang Liu |
| author_sort | Bing Li |
| collection | DOAJ |
| description | Abstract This study aims to explore the relationship between the Triglyceride Glucose Body Mass Index (TyG-BMI) and the risk of developing benign prostatic hyperplasia (BPH). Utilizing data from the China Health and Retirement Longitudinal Study (CHARLS), we included 3301 men aged 45 and above. We analyzed the association between TyG-BMI and the risk of developing BPH using multivariable logistic regression and restricted cubic spline models. During the 4-year follow-up period, 268 cases of BPH were identified. There was a positive correlation between TyG-BMI and the risk of BPH (OR 1.22, 95% CI 1.08–1.38, p < 0.001), with a significant dose-response relationship (P < 0.001). Stratified analyses indicated that the impact of TyG-BMI on BPH risk was consistent across various subgroups. There is a linear positive correlation between TyG-BMI and the risk of developing BPH. Managing TyG-BMI levels may help reduce the risk of BPH. |
| format | Article |
| id | doaj-art-2b71ac12c1b44b12969b1f67ed16a522 |
| institution | DOAJ |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-2b71ac12c1b44b12969b1f67ed16a5222025-08-20T02:56:09ZengNature PortfolioScientific Reports2045-23222025-03-011511910.1038/s41598-024-81629-yAssociation between TyG-BMI and BPH in a national prospective cohort studyBing Li0Zhiqiang Zhang1Chao Sun2Yaodong Sun3Junping Li4Xiaoqiang Liu5Department of Urology, Tianjin Medical University General HospitalGraduate School of Tianjin Medical University, Tianjin Medical UniversityDepartment of Orthopaedics, Tianjin Medical University General HospitalDepartment of Cardiovascular surgery, Tianjin Medical University General HospitalDepartment of Oncology, Zibo City Municipal HospitalDepartment of Urology, Tianjin Medical University General HospitalAbstract This study aims to explore the relationship between the Triglyceride Glucose Body Mass Index (TyG-BMI) and the risk of developing benign prostatic hyperplasia (BPH). Utilizing data from the China Health and Retirement Longitudinal Study (CHARLS), we included 3301 men aged 45 and above. We analyzed the association between TyG-BMI and the risk of developing BPH using multivariable logistic regression and restricted cubic spline models. During the 4-year follow-up period, 268 cases of BPH were identified. There was a positive correlation between TyG-BMI and the risk of BPH (OR 1.22, 95% CI 1.08–1.38, p < 0.001), with a significant dose-response relationship (P < 0.001). Stratified analyses indicated that the impact of TyG-BMI on BPH risk was consistent across various subgroups. There is a linear positive correlation between TyG-BMI and the risk of developing BPH. Managing TyG-BMI levels may help reduce the risk of BPH.https://doi.org/10.1038/s41598-024-81629-yTyG-BMI indexBenign prostatic hyperplasiaCohort studyLinear response relationshipChina health and retirement longitudinal study |
| spellingShingle | Bing Li Zhiqiang Zhang Chao Sun Yaodong Sun Junping Li Xiaoqiang Liu Association between TyG-BMI and BPH in a national prospective cohort study Scientific Reports TyG-BMI index Benign prostatic hyperplasia Cohort study Linear response relationship China health and retirement longitudinal study |
| title | Association between TyG-BMI and BPH in a national prospective cohort study |
| title_full | Association between TyG-BMI and BPH in a national prospective cohort study |
| title_fullStr | Association between TyG-BMI and BPH in a national prospective cohort study |
| title_full_unstemmed | Association between TyG-BMI and BPH in a national prospective cohort study |
| title_short | Association between TyG-BMI and BPH in a national prospective cohort study |
| title_sort | association between tyg bmi and bph in a national prospective cohort study |
| topic | TyG-BMI index Benign prostatic hyperplasia Cohort study Linear response relationship China health and retirement longitudinal study |
| url | https://doi.org/10.1038/s41598-024-81629-y |
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