Values of some topographic parameters of optic nerve head obtained by Heidelberg retina tomograph II in volunteers and different stage primary open-angle glaucoma patients

Purpose: То assess the values of the top five topographic parameters of optic nerve head (ONH) obtained by Heidelberg retina tomograph (HRT) II in volunteers and primary open angle glaucoma (POAG) patients with different stage of perimetric changes.Methods: 73 eyes (38 volunteers at the age of 56 ye...

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Main Authors: B. Anguelov, A. Toshev
Format: Article
Language:Russian
Published: Ophthalmology Publishing Group 2014-07-01
Series:Oftalʹmologiâ
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Online Access:https://www.ophthalmojournal.com/opht/article/view/106
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author B. Anguelov
A. Toshev
author_facet B. Anguelov
A. Toshev
author_sort B. Anguelov
collection DOAJ
description Purpose: То assess the values of the top five topographic parameters of optic nerve head (ONH) obtained by Heidelberg retina tomograph (HRT) II in volunteers and primary open angle glaucoma (POAG) patients with different stage of perimetric changes.Methods: 73 eyes (38 volunteers at the age of 56 years ±13, 11 men and 27 women) and 170 eyes (90 patients at the age of 66 years ±12, 33 men and 57 women) were examined. We performed the comprehensive ophthalmic examination, standard automated perimetry and measurement of the top five topographic parameters of ONH — rim area, rim volume, cup shape measure, height variation contour и mean RNFL thickness. For the purpose of this study we used HRT II.Results: We determine the values of the investigated topographic parameters of the ONH for healthy volunteers (rim area = 1.68±0.22 mm2, rim volume = 0.44±0.07 mm3, cup shape measure = –0.2±0.06, height variation contour = 0.38±0.08 mm and mean RNFL thickness = 0.24±0.03 mm) and for the patients in different perimetric glaucoma stages (early stage: rim area = 1.52±0.47 mm2, rim volume = 0.38±0.17 mm3, cup shape measure = –0.14±0.1, height variation contour = 0.36±0.09 mm and mean RNFL thickness = 0.22±0.11 mm; moderate stage: rim area = 1.21±0.46 mm2, rim volume = 0.27±0.17 mm3, cup shape measure = –0.09±0.1, height variation contour = 0.36±0.17 mm and mean RNFL thickness = 0.16±0.12 mm; severe stage: rim area = 0.97±0.01 mm2, rim volume = 0.18±0.17 mm3, cup shape measure = –0.06±0.1, height variation contour = 0.28±0.11 mm and mean RNFL thickness = 0.17±0.11 mm). Hodapp-Parrish-Anderson (H-P-A) ’s staging system includes three separate levels (early, moderate and severe) of glaucoma according to visual field defects. Each stage is additionally characterized by the values of the top five topographic parameters of the ONH.Conclusion: Early diagnosis, staging and follow-up of POAG are based on both function and structure assessment. The created value intervals for the top five topographic parameters of the ONH for healthy volunteers and patients in different perimetric stages of glaucoma help and support their right classification. Patients with different level changes require different kind of treatment at different price. In this respect the acquired data is an initial step at the development of POAG staging system based on the topographic parameters of ONH obtained by HRT II.
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spelling doaj-art-2b6ef3653cc44d36a4032b68a8ea4e142025-08-20T03:22:19ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452014-07-01103404510.18008/1816-5095-2013-3-40-45106Values of some topographic parameters of optic nerve head obtained by Heidelberg retina tomograph II in volunteers and different stage primary open-angle glaucoma patientsB. Anguelov0A. Toshev1МУ, УМБАЛ «Александровская»МУ, УМБАЛ «Александровская»Purpose: То assess the values of the top five topographic parameters of optic nerve head (ONH) obtained by Heidelberg retina tomograph (HRT) II in volunteers and primary open angle glaucoma (POAG) patients with different stage of perimetric changes.Methods: 73 eyes (38 volunteers at the age of 56 years ±13, 11 men and 27 women) and 170 eyes (90 patients at the age of 66 years ±12, 33 men and 57 women) were examined. We performed the comprehensive ophthalmic examination, standard automated perimetry and measurement of the top five topographic parameters of ONH — rim area, rim volume, cup shape measure, height variation contour и mean RNFL thickness. For the purpose of this study we used HRT II.Results: We determine the values of the investigated topographic parameters of the ONH for healthy volunteers (rim area = 1.68±0.22 mm2, rim volume = 0.44±0.07 mm3, cup shape measure = –0.2±0.06, height variation contour = 0.38±0.08 mm and mean RNFL thickness = 0.24±0.03 mm) and for the patients in different perimetric glaucoma stages (early stage: rim area = 1.52±0.47 mm2, rim volume = 0.38±0.17 mm3, cup shape measure = –0.14±0.1, height variation contour = 0.36±0.09 mm and mean RNFL thickness = 0.22±0.11 mm; moderate stage: rim area = 1.21±0.46 mm2, rim volume = 0.27±0.17 mm3, cup shape measure = –0.09±0.1, height variation contour = 0.36±0.17 mm and mean RNFL thickness = 0.16±0.12 mm; severe stage: rim area = 0.97±0.01 mm2, rim volume = 0.18±0.17 mm3, cup shape measure = –0.06±0.1, height variation contour = 0.28±0.11 mm and mean RNFL thickness = 0.17±0.11 mm). Hodapp-Parrish-Anderson (H-P-A) ’s staging system includes three separate levels (early, moderate and severe) of glaucoma according to visual field defects. Each stage is additionally characterized by the values of the top five topographic parameters of the ONH.Conclusion: Early diagnosis, staging and follow-up of POAG are based on both function and structure assessment. The created value intervals for the top five topographic parameters of the ONH for healthy volunteers and patients in different perimetric stages of glaucoma help and support their right classification. Patients with different level changes require different kind of treatment at different price. In this respect the acquired data is an initial step at the development of POAG staging system based on the topographic parameters of ONH obtained by HRT II.https://www.ophthalmojournal.com/opht/article/view/106primary open-angle glaucomatopographic parametersheidelberg retina tomograph iistandard automated perimety.
spellingShingle B. Anguelov
A. Toshev
Values of some topographic parameters of optic nerve head obtained by Heidelberg retina tomograph II in volunteers and different stage primary open-angle glaucoma patients
Oftalʹmologiâ
primary open-angle glaucoma
topographic parameters
heidelberg retina tomograph ii
standard automated perimety.
title Values of some topographic parameters of optic nerve head obtained by Heidelberg retina tomograph II in volunteers and different stage primary open-angle glaucoma patients
title_full Values of some topographic parameters of optic nerve head obtained by Heidelberg retina tomograph II in volunteers and different stage primary open-angle glaucoma patients
title_fullStr Values of some topographic parameters of optic nerve head obtained by Heidelberg retina tomograph II in volunteers and different stage primary open-angle glaucoma patients
title_full_unstemmed Values of some topographic parameters of optic nerve head obtained by Heidelberg retina tomograph II in volunteers and different stage primary open-angle glaucoma patients
title_short Values of some topographic parameters of optic nerve head obtained by Heidelberg retina tomograph II in volunteers and different stage primary open-angle glaucoma patients
title_sort values of some topographic parameters of optic nerve head obtained by heidelberg retina tomograph ii in volunteers and different stage primary open angle glaucoma patients
topic primary open-angle glaucoma
topographic parameters
heidelberg retina tomograph ii
standard automated perimety.
url https://www.ophthalmojournal.com/opht/article/view/106
work_keys_str_mv AT banguelov valuesofsometopographicparametersofopticnerveheadobtainedbyheidelbergretinatomographiiinvolunteersanddifferentstageprimaryopenangleglaucomapatients
AT atoshev valuesofsometopographicparametersofopticnerveheadobtainedbyheidelbergretinatomographiiinvolunteersanddifferentstageprimaryopenangleglaucomapatients