Comparative Analysis of the Effects of Crude Metabolic Extracts of Three Biocontrol Bacteria on Microbial Community Structure Provides a New Strategy for the Biological Control of Apple Replant Disease

The crude metabolic extract from plant biocontrol bacteria plays a very important role in sustainable agricultural production. These extracts help maintain healthy plants and have very important application prospects in biotechnology related to alleviating apple replant disease (ARD). In this study,...

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Main Authors: Jinhui Lv, Weitao Jiang, Zihui Xu, Gongshuai Wang, Xiaoxuan Li, Xinyu Wu, Fengxia Ding, Yusong Liu, Xuesen Chen, Chengmiao Yin, Zhiquan Mao
Format: Article
Language:English
Published: MDPI AG 2024-09-01
Series:Horticulturae
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Online Access:https://www.mdpi.com/2311-7524/10/10/1035
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author Jinhui Lv
Weitao Jiang
Zihui Xu
Gongshuai Wang
Xiaoxuan Li
Xinyu Wu
Fengxia Ding
Yusong Liu
Xuesen Chen
Chengmiao Yin
Zhiquan Mao
author_facet Jinhui Lv
Weitao Jiang
Zihui Xu
Gongshuai Wang
Xiaoxuan Li
Xinyu Wu
Fengxia Ding
Yusong Liu
Xuesen Chen
Chengmiao Yin
Zhiquan Mao
author_sort Jinhui Lv
collection DOAJ
description The crude metabolic extract from plant biocontrol bacteria plays a very important role in sustainable agricultural production. These extracts help maintain healthy plants and have very important application prospects in biotechnology related to alleviating apple replant disease (ARD). In this study, <i>Bacillus velezensis</i> XC1 (T1), <i>Bacillus amyloliquefaciens</i> QSB-6 (T2), and <i>Lactobacillus reuteri</i> LBR (T3) were examined to characterize the ability of their crude metabolic extracts to alleviate ARD. The high-throughput sequencing data of the soil microbial community structure were analyzed in relation to LBR crude metabolic extracts, and an extensive untargeted metabolomic analysis of UHPLC-Qex active components was performed. Active LC-MS/MS revealed that the main secondary metabolites involved in the biological control exerted by <i>L. reuteri</i> included 3-hydroxypropionaldehyde, extracellular polysaccharides (EPS), p-hydroxybenzoic acid, and azelaic acid. These crude metabolic extracts significantly inhibited the growth of soil pathogenic fungi, reduced the abundance of <i>Fusarium</i>, promoted the abundance of beneficial bacteria such as <i>Pseudomonas</i>, and optimized the soil microbial community structure. Improved modern extraction and purification technologies will be able to offer additional insights into the mechanism of action of these secondary metabolites and enable them to be used in biological preparations to prevent and control ARD in the future, as well as to allow harmful chemical fumigants to be discontinued.
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spelling doaj-art-2b6e0b15b03e4945a21da2b3f118b7702025-08-20T02:11:12ZengMDPI AGHorticulturae2311-75242024-09-011010103510.3390/horticulturae10101035Comparative Analysis of the Effects of Crude Metabolic Extracts of Three Biocontrol Bacteria on Microbial Community Structure Provides a New Strategy for the Biological Control of Apple Replant DiseaseJinhui Lv0Weitao Jiang1Zihui Xu2Gongshuai Wang3Xiaoxuan Li4Xinyu Wu5Fengxia Ding6Yusong Liu7Xuesen Chen8Chengmiao Yin9Zhiquan Mao10College of Horticulture Science, Engineering Shandong Agricultural University, Tai’an 271018, ChinaCollege of Horticulture Science, Engineering Shandong Agricultural University, Tai’an 271018, ChinaCollege of Horticulture Science, Engineering Shandong Agricultural University, Tai’an 271018, ChinaCollege of Agricultural Science and Technology, Shandong Agriculture and Engineering University, Jinan 251100, ChinaCollege of Horticulture Science, Engineering Shandong Agricultural University, Tai’an 271018, ChinaCollege of Horticulture Science, Engineering Shandong Agricultural University, Tai’an 271018, ChinaWudi County Jieshi Shan Town Agricultural Comprehensive Service Center, Binzhou 251910, ChinaCollege of Horticulture Science, Engineering Shandong Agricultural University, Tai’an 271018, ChinaCollege of Horticulture Science, Engineering Shandong Agricultural University, Tai’an 271018, ChinaCollege of Horticulture Science, Engineering Shandong Agricultural University, Tai’an 271018, ChinaCollege of Horticulture Science, Engineering Shandong Agricultural University, Tai’an 271018, ChinaThe crude metabolic extract from plant biocontrol bacteria plays a very important role in sustainable agricultural production. These extracts help maintain healthy plants and have very important application prospects in biotechnology related to alleviating apple replant disease (ARD). In this study, <i>Bacillus velezensis</i> XC1 (T1), <i>Bacillus amyloliquefaciens</i> QSB-6 (T2), and <i>Lactobacillus reuteri</i> LBR (T3) were examined to characterize the ability of their crude metabolic extracts to alleviate ARD. The high-throughput sequencing data of the soil microbial community structure were analyzed in relation to LBR crude metabolic extracts, and an extensive untargeted metabolomic analysis of UHPLC-Qex active components was performed. Active LC-MS/MS revealed that the main secondary metabolites involved in the biological control exerted by <i>L. reuteri</i> included 3-hydroxypropionaldehyde, extracellular polysaccharides (EPS), p-hydroxybenzoic acid, and azelaic acid. These crude metabolic extracts significantly inhibited the growth of soil pathogenic fungi, reduced the abundance of <i>Fusarium</i>, promoted the abundance of beneficial bacteria such as <i>Pseudomonas</i>, and optimized the soil microbial community structure. Improved modern extraction and purification technologies will be able to offer additional insights into the mechanism of action of these secondary metabolites and enable them to be used in biological preparations to prevent and control ARD in the future, as well as to allow harmful chemical fumigants to be discontinued.https://www.mdpi.com/2311-7524/10/10/1035appleapple replant disease<i>Lactobacillus reuteri</i>crude metabolic extractmicrobial community structure
spellingShingle Jinhui Lv
Weitao Jiang
Zihui Xu
Gongshuai Wang
Xiaoxuan Li
Xinyu Wu
Fengxia Ding
Yusong Liu
Xuesen Chen
Chengmiao Yin
Zhiquan Mao
Comparative Analysis of the Effects of Crude Metabolic Extracts of Three Biocontrol Bacteria on Microbial Community Structure Provides a New Strategy for the Biological Control of Apple Replant Disease
Horticulturae
apple
apple replant disease
<i>Lactobacillus reuteri</i>
crude metabolic extract
microbial community structure
title Comparative Analysis of the Effects of Crude Metabolic Extracts of Three Biocontrol Bacteria on Microbial Community Structure Provides a New Strategy for the Biological Control of Apple Replant Disease
title_full Comparative Analysis of the Effects of Crude Metabolic Extracts of Three Biocontrol Bacteria on Microbial Community Structure Provides a New Strategy for the Biological Control of Apple Replant Disease
title_fullStr Comparative Analysis of the Effects of Crude Metabolic Extracts of Three Biocontrol Bacteria on Microbial Community Structure Provides a New Strategy for the Biological Control of Apple Replant Disease
title_full_unstemmed Comparative Analysis of the Effects of Crude Metabolic Extracts of Three Biocontrol Bacteria on Microbial Community Structure Provides a New Strategy for the Biological Control of Apple Replant Disease
title_short Comparative Analysis of the Effects of Crude Metabolic Extracts of Three Biocontrol Bacteria on Microbial Community Structure Provides a New Strategy for the Biological Control of Apple Replant Disease
title_sort comparative analysis of the effects of crude metabolic extracts of three biocontrol bacteria on microbial community structure provides a new strategy for the biological control of apple replant disease
topic apple
apple replant disease
<i>Lactobacillus reuteri</i>
crude metabolic extract
microbial community structure
url https://www.mdpi.com/2311-7524/10/10/1035
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