Fabrication and Characterization of a Novel Solid Nano-Dispersion of Emamectin Benzoate with High Dispersibility and Wettability

Pesticides, as an indispensable component in agricultural production, play a crucial role in ensuring global food security. However, the low efficiency of pesticide utilization remains a significant challenge. The key method of improving the effective utilization rate of pesticides is mainly to enha...

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Main Authors: Ying Li, Qing Wang, Junqian Pan, Xiang Zhao, Jinghui Zhan, Xinglong Xu, Meng Zhang, Chunxin Wang, Haixin Cui
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Nanomaterials
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Online Access:https://www.mdpi.com/2079-4991/15/7/495
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author Ying Li
Qing Wang
Junqian Pan
Xiang Zhao
Jinghui Zhan
Xinglong Xu
Meng Zhang
Chunxin Wang
Haixin Cui
author_facet Ying Li
Qing Wang
Junqian Pan
Xiang Zhao
Jinghui Zhan
Xinglong Xu
Meng Zhang
Chunxin Wang
Haixin Cui
author_sort Ying Li
collection DOAJ
description Pesticides, as an indispensable component in agricultural production, play a crucial role in ensuring global food security. However, the low efficiency of pesticide utilization remains a significant challenge. The key method of improving the effective utilization rate of pesticides is mainly to enhance the affinity between pesticides and leaf surfaces while improving their deposition and adhesion properties. In this study, we utilized PEG 4000 as a carrier and emulsifier 600 and emulsifiers 700 as surfactants to prepare solid nano-dispersion of emamectin benzoate (SND-EB) by the melting method. SND-EB particles were spherical with an average diameter of 17 nm, a loading capacity of up to 50%, and excellent dispersibility. Contact angle and bouncing behavior tests on cabbage and pepper leaves demonstrated that SND-EB had superior wetting properties and spreading capabilities. Surface tension and leaf retention measurements further confirmed that SND-EB possessed excellent adhesion and leaf affinity. The SND-EB showed a 1.8-fold increase in biological activity against <i>Spodoptera exigua</i> compared to commercial emamectin benzoate water-dispersible granule (WDG-EB). In addition, the fabricated nanoparticles exerted no toxic effect on HepG2 cells. These results demonstrated that a 50% content of SND-EB exhibited excellent water dispersity, wettability, and insecticidal activity, providing a novel and efficient strategy for pest control.
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spelling doaj-art-2b6a15e0fa6e4477a8cb38168f37f68c2025-08-20T03:03:21ZengMDPI AGNanomaterials2079-49912025-03-0115749510.3390/nano15070495Fabrication and Characterization of a Novel Solid Nano-Dispersion of Emamectin Benzoate with High Dispersibility and WettabilityYing Li0Qing Wang1Junqian Pan2Xiang Zhao3Jinghui Zhan4Xinglong Xu5Meng Zhang6Chunxin Wang7Haixin Cui8College of Resources and Environment, Shanxi Agricultural University, Taigu 030800, ChinaCollege of Resources and Environment, Shanxi Agricultural University, Taigu 030800, ChinaInstitute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, ChinaInstitute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, ChinaInstitute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, ChinaInstitute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, ChinaInstitute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, ChinaInstitute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, ChinaInstitute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, ChinaPesticides, as an indispensable component in agricultural production, play a crucial role in ensuring global food security. However, the low efficiency of pesticide utilization remains a significant challenge. The key method of improving the effective utilization rate of pesticides is mainly to enhance the affinity between pesticides and leaf surfaces while improving their deposition and adhesion properties. In this study, we utilized PEG 4000 as a carrier and emulsifier 600 and emulsifiers 700 as surfactants to prepare solid nano-dispersion of emamectin benzoate (SND-EB) by the melting method. SND-EB particles were spherical with an average diameter of 17 nm, a loading capacity of up to 50%, and excellent dispersibility. Contact angle and bouncing behavior tests on cabbage and pepper leaves demonstrated that SND-EB had superior wetting properties and spreading capabilities. Surface tension and leaf retention measurements further confirmed that SND-EB possessed excellent adhesion and leaf affinity. The SND-EB showed a 1.8-fold increase in biological activity against <i>Spodoptera exigua</i> compared to commercial emamectin benzoate water-dispersible granule (WDG-EB). In addition, the fabricated nanoparticles exerted no toxic effect on HepG2 cells. These results demonstrated that a 50% content of SND-EB exhibited excellent water dispersity, wettability, and insecticidal activity, providing a novel and efficient strategy for pest control.https://www.mdpi.com/2079-4991/15/7/495nanopesticidesemamectin benzoatedispersibilitywettabilitysolid nano-dispersion
spellingShingle Ying Li
Qing Wang
Junqian Pan
Xiang Zhao
Jinghui Zhan
Xinglong Xu
Meng Zhang
Chunxin Wang
Haixin Cui
Fabrication and Characterization of a Novel Solid Nano-Dispersion of Emamectin Benzoate with High Dispersibility and Wettability
Nanomaterials
nanopesticides
emamectin benzoate
dispersibility
wettability
solid nano-dispersion
title Fabrication and Characterization of a Novel Solid Nano-Dispersion of Emamectin Benzoate with High Dispersibility and Wettability
title_full Fabrication and Characterization of a Novel Solid Nano-Dispersion of Emamectin Benzoate with High Dispersibility and Wettability
title_fullStr Fabrication and Characterization of a Novel Solid Nano-Dispersion of Emamectin Benzoate with High Dispersibility and Wettability
title_full_unstemmed Fabrication and Characterization of a Novel Solid Nano-Dispersion of Emamectin Benzoate with High Dispersibility and Wettability
title_short Fabrication and Characterization of a Novel Solid Nano-Dispersion of Emamectin Benzoate with High Dispersibility and Wettability
title_sort fabrication and characterization of a novel solid nano dispersion of emamectin benzoate with high dispersibility and wettability
topic nanopesticides
emamectin benzoate
dispersibility
wettability
solid nano-dispersion
url https://www.mdpi.com/2079-4991/15/7/495
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