Branch Retinal Artery Occlusion as a Presenting Feature of Anti-Phospholipid Antibody Syndrome and Homocysteinemia

Retinal artery occlusion (RAO) is an uncommon presentation at a young age. In contrast to retinal artery occlusion in the elderly, where the most common mechanism of occlusion involves embolic disease from the carotid artery, RAO in young adults occur secondary to a diverse group of pathologic condi...

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Main Authors: Richa Agarwal, Vikas Veerwal, Parul Jain, J L Goyal, Neha Jain
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-07-01
Series:Delhi Journal of Ophthalmology
Subjects:
Online Access:https://journals.lww.com/10.7869/djo.132
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author Richa Agarwal
Vikas Veerwal
Parul Jain
J L Goyal
Neha Jain
author_facet Richa Agarwal
Vikas Veerwal
Parul Jain
J L Goyal
Neha Jain
author_sort Richa Agarwal
collection DOAJ
description Retinal artery occlusion (RAO) is an uncommon presentation at a young age. In contrast to retinal artery occlusion in the elderly, where the most common mechanism of occlusion involves embolic disease from the carotid artery, RAO in young adults occur secondary to a diverse group of pathologic conditions, like hypercoagulable states leading to thrombosis, antiphospholipid syndrome (APS), elevated homocysteine levels. We report a unique case of a young female who presented with decreased vision in her right eye due to a branch RAO. Thorough systemic evaluation led to a diagnosis of APS along with presence of hyperhomocysteinemia and Rheumatic Heart Disease. Patient was advised warfarin therapy along with vitamin supplementation to reduce the risk of further thrombotic events. By means of this report, we would like to highlight that the high prevalence of underlying systemic disease in young patients with RAO necessitates a thorough, aggressive examination to rule out potential life-threatening embolic and hypercoagulable conditions.
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institution DOAJ
issn 0972-0200
2454-2784
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publishDate 2015-07-01
publisher Wolters Kluwer Medknow Publications
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series Delhi Journal of Ophthalmology
spelling doaj-art-2b6410e38d2f4afdb1d73f30dbd85cc52025-08-20T03:11:07ZengWolters Kluwer Medknow PublicationsDelhi Journal of Ophthalmology0972-02002454-27842015-07-01261343610.7869/djo.132Branch Retinal Artery Occlusion as a Presenting Feature of Anti-Phospholipid Antibody Syndrome and HomocysteinemiaRicha AgarwalVikas VeerwalParul JainJ L GoyalNeha JainRetinal artery occlusion (RAO) is an uncommon presentation at a young age. In contrast to retinal artery occlusion in the elderly, where the most common mechanism of occlusion involves embolic disease from the carotid artery, RAO in young adults occur secondary to a diverse group of pathologic conditions, like hypercoagulable states leading to thrombosis, antiphospholipid syndrome (APS), elevated homocysteine levels. We report a unique case of a young female who presented with decreased vision in her right eye due to a branch RAO. Thorough systemic evaluation led to a diagnosis of APS along with presence of hyperhomocysteinemia and Rheumatic Heart Disease. Patient was advised warfarin therapy along with vitamin supplementation to reduce the risk of further thrombotic events. By means of this report, we would like to highlight that the high prevalence of underlying systemic disease in young patients with RAO necessitates a thorough, aggressive examination to rule out potential life-threatening embolic and hypercoagulable conditions.https://journals.lww.com/10.7869/djo.132braoapla syndromehomocysteinemia
spellingShingle Richa Agarwal
Vikas Veerwal
Parul Jain
J L Goyal
Neha Jain
Branch Retinal Artery Occlusion as a Presenting Feature of Anti-Phospholipid Antibody Syndrome and Homocysteinemia
Delhi Journal of Ophthalmology
brao
apla syndrome
homocysteinemia
title Branch Retinal Artery Occlusion as a Presenting Feature of Anti-Phospholipid Antibody Syndrome and Homocysteinemia
title_full Branch Retinal Artery Occlusion as a Presenting Feature of Anti-Phospholipid Antibody Syndrome and Homocysteinemia
title_fullStr Branch Retinal Artery Occlusion as a Presenting Feature of Anti-Phospholipid Antibody Syndrome and Homocysteinemia
title_full_unstemmed Branch Retinal Artery Occlusion as a Presenting Feature of Anti-Phospholipid Antibody Syndrome and Homocysteinemia
title_short Branch Retinal Artery Occlusion as a Presenting Feature of Anti-Phospholipid Antibody Syndrome and Homocysteinemia
title_sort branch retinal artery occlusion as a presenting feature of anti phospholipid antibody syndrome and homocysteinemia
topic brao
apla syndrome
homocysteinemia
url https://journals.lww.com/10.7869/djo.132
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AT vikasveerwal branchretinalarteryocclusionasapresentingfeatureofantiphospholipidantibodysyndromeandhomocysteinemia
AT paruljain branchretinalarteryocclusionasapresentingfeatureofantiphospholipidantibodysyndromeandhomocysteinemia
AT jlgoyal branchretinalarteryocclusionasapresentingfeatureofantiphospholipidantibodysyndromeandhomocysteinemia
AT nehajain branchretinalarteryocclusionasapresentingfeatureofantiphospholipidantibodysyndromeandhomocysteinemia