A Multi Center, Epidemiological Study of Bone Tuberculosis in Southwest China from 2011 to 2023
Abstract Background Despite continued efforts to manage and control Tuberculosis (TB) in China, it remains a major health concern. Bone tuberculosis (Bone-TB), a common form of extrapulmonary tuberculosis, still adds considerably to the global TB case load. Diagnosing Bone-TB is often difficult as i...
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Springer
2024-11-01
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| Series: | Journal of Epidemiology and Global Health |
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| Online Access: | https://doi.org/10.1007/s44197-024-00325-2 |
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| author | Xiaopeng Qin Boli Qin Chenxing Zhou Chong Liu Tianyou Chen Jichong Zhu Chengqian Huang Shaofeng Wu Rongqing He Songze Wu Sitan Feng Jiarui Chen Jiang Xue Wendi Wei Liyi Chen Kechang He Zhendong Qin Tiejun Zhou Jie Ma Xinli Zhan |
| author_facet | Xiaopeng Qin Boli Qin Chenxing Zhou Chong Liu Tianyou Chen Jichong Zhu Chengqian Huang Shaofeng Wu Rongqing He Songze Wu Sitan Feng Jiarui Chen Jiang Xue Wendi Wei Liyi Chen Kechang He Zhendong Qin Tiejun Zhou Jie Ma Xinli Zhan |
| author_sort | Xiaopeng Qin |
| collection | DOAJ |
| description | Abstract Background Despite continued efforts to manage and control Tuberculosis (TB) in China, it remains a major health concern. Bone tuberculosis (Bone-TB), a common form of extrapulmonary tuberculosis, still adds considerably to the global TB case load. Diagnosing Bone-TB is often difficult as its symptoms can be similar to other bone or joint diseases, which leads to delayed detection and treatment. Currently, comprehensive reports on the epidemiological aspects of Bone-TB in China are scarce. Methods This retrospective study analyzed demographic and clinical data from 2,191 patients diagnosed with Bone-TB in Southwest China between January 2011 and September 2023.This study fully reveals the characteristics of Bone-TB in Southwest China. Results The overall trend of bone tuberculosis was a slow rise. Among 2191 patients, males, farmers, aged 42–68 years, and people with HIV and diabetes are the priority groups for the prevention and treatment of Bone-TB. The majority of the infected spines (1556/2191) were located in the thoracic vertebra (759/2191) and lumbar vertebra (715/2191). Forty-nine (2.24%) patients had drug-resistant TB (DR-TB). Forty-five (2.05%) died during the treatment. The total and actual hospitalization. Costs amounted to $3,837.10 and $1,914.35 (p < 0.01). Patients with DR-TB incurred the highest costs, amounting to $4,968.37. Cervical TB, with a prevalence of 5 patients (6.10%), exhibited the highest rates of catastrophic expenditures. Conclusions From 2011 to 2023, the yearly occurrence of Bone-TB in southwestern China exhibited a rising pattern, marked by notable distinctions in terms of gender, age, and regional variations, indicating localized clustering characteristics. |
| format | Article |
| id | doaj-art-2b61b3f09a26408690c55411ebc4bee3 |
| institution | OA Journals |
| issn | 2210-6014 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Springer |
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| series | Journal of Epidemiology and Global Health |
| spelling | doaj-art-2b61b3f09a26408690c55411ebc4bee32025-08-20T02:31:54ZengSpringerJournal of Epidemiology and Global Health2210-60142024-11-011441678169210.1007/s44197-024-00325-2A Multi Center, Epidemiological Study of Bone Tuberculosis in Southwest China from 2011 to 2023Xiaopeng Qin0Boli Qin1Chenxing Zhou2Chong Liu3Tianyou Chen4Jichong Zhu5Chengqian Huang6Shaofeng Wu7Rongqing He8Songze Wu9Sitan Feng10Jiarui Chen11Jiang Xue12Wendi Wei13Liyi Chen14Kechang He15Zhendong Qin16Tiejun Zhou17Jie Ma18Xinli Zhan19The First Affiliated Hospital of Guangxi Medical UniversityThe First Affiliated Hospital of Guangxi Medical UniversityThe First Affiliated Hospital of Guangxi Medical UniversityThe First Affiliated Hospital of Guangxi Medical UniversityThe First Affiliated Hospital of Guangxi Medical UniversityThe First Affiliated Hospital of Guangxi Medical UniversityThe First Affiliated Hospital of Guangxi Medical UniversityThe First Affiliated Hospital of Guangxi Medical UniversityThe First Affiliated Hospital of Guangxi Medical UniversityThe First Affiliated Hospital of Guangxi Medical UniversityThe First Affiliated Hospital of Guangxi Medical UniversityThe First Affiliated Hospital of Guangxi Medical UniversityThe First Affiliated Hospital of Guangxi Medical UniversityThe First Affiliated Hospital of Guangxi Medical UniversityThe First Affiliated Hospital of Guangxi Medical UniversityThe Fourth People’s Hospital of NanningThe Fourth People’s Hospital of NanningThe Fourth People’s Hospital of NanningThe Fourth People’s Hospital of NanningThe First Affiliated Hospital of Guangxi Medical UniversityAbstract Background Despite continued efforts to manage and control Tuberculosis (TB) in China, it remains a major health concern. Bone tuberculosis (Bone-TB), a common form of extrapulmonary tuberculosis, still adds considerably to the global TB case load. Diagnosing Bone-TB is often difficult as its symptoms can be similar to other bone or joint diseases, which leads to delayed detection and treatment. Currently, comprehensive reports on the epidemiological aspects of Bone-TB in China are scarce. Methods This retrospective study analyzed demographic and clinical data from 2,191 patients diagnosed with Bone-TB in Southwest China between January 2011 and September 2023.This study fully reveals the characteristics of Bone-TB in Southwest China. Results The overall trend of bone tuberculosis was a slow rise. Among 2191 patients, males, farmers, aged 42–68 years, and people with HIV and diabetes are the priority groups for the prevention and treatment of Bone-TB. The majority of the infected spines (1556/2191) were located in the thoracic vertebra (759/2191) and lumbar vertebra (715/2191). Forty-nine (2.24%) patients had drug-resistant TB (DR-TB). Forty-five (2.05%) died during the treatment. The total and actual hospitalization. Costs amounted to $3,837.10 and $1,914.35 (p < 0.01). Patients with DR-TB incurred the highest costs, amounting to $4,968.37. Cervical TB, with a prevalence of 5 patients (6.10%), exhibited the highest rates of catastrophic expenditures. Conclusions From 2011 to 2023, the yearly occurrence of Bone-TB in southwestern China exhibited a rising pattern, marked by notable distinctions in terms of gender, age, and regional variations, indicating localized clustering characteristics.https://doi.org/10.1007/s44197-024-00325-2Epidemiological characteristicsBone-TBDrug resistanceDisease burdenCost assessment |
| spellingShingle | Xiaopeng Qin Boli Qin Chenxing Zhou Chong Liu Tianyou Chen Jichong Zhu Chengqian Huang Shaofeng Wu Rongqing He Songze Wu Sitan Feng Jiarui Chen Jiang Xue Wendi Wei Liyi Chen Kechang He Zhendong Qin Tiejun Zhou Jie Ma Xinli Zhan A Multi Center, Epidemiological Study of Bone Tuberculosis in Southwest China from 2011 to 2023 Journal of Epidemiology and Global Health Epidemiological characteristics Bone-TB Drug resistance Disease burden Cost assessment |
| title | A Multi Center, Epidemiological Study of Bone Tuberculosis in Southwest China from 2011 to 2023 |
| title_full | A Multi Center, Epidemiological Study of Bone Tuberculosis in Southwest China from 2011 to 2023 |
| title_fullStr | A Multi Center, Epidemiological Study of Bone Tuberculosis in Southwest China from 2011 to 2023 |
| title_full_unstemmed | A Multi Center, Epidemiological Study of Bone Tuberculosis in Southwest China from 2011 to 2023 |
| title_short | A Multi Center, Epidemiological Study of Bone Tuberculosis in Southwest China from 2011 to 2023 |
| title_sort | multi center epidemiological study of bone tuberculosis in southwest china from 2011 to 2023 |
| topic | Epidemiological characteristics Bone-TB Drug resistance Disease burden Cost assessment |
| url | https://doi.org/10.1007/s44197-024-00325-2 |
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