Regional quantification of metabolic liver function using hyperpolarized [1-13C] pyruvate MRI

Regional quantification of metabolic liver function using hyperpolarized [1-13C] pyruvate MRI

Abstract Assessment of liver function is essential before partial hepatectomy to predict the risk of post hepatectomy liver failure, a severe and life-threatening complication. Traditional methods have focused on expected future liver remnant (FLR) volume estimation. However, liver volume does not a...

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Bibliographic Details
Main Authors: Uffe Kjaergaard, Andrea Lund, Mohsen Redda, Mattias Hedegaard Kristensen, Malene Aastrup, Nikolaj Bøgh, Kim Sivesgaard, Michael A. Ohliger, Daniel B. Vigneron, Lotte Bonde Bertelsen, Aage Kristian Olsen Alstrup, Esben Søvsø Szocska Hansen, Frank Viborg Mortensen, Christoffer Laustsen
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Magnetic resonance imaging
Hyperpolarized
Lactate dehydrogenase (LDH)
Alanine aminotransferase (ALT)
Liver regeneration
Portal vein ligation
Online Access:https://doi.org/10.1038/s41598-025-93725-8
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