The effect of Cd2+ ions on the passive permeability of the mitochondrial membrane of liver cell of Rats

This article describes the results of a study conducted on rats on the effects of heavy metal salts, including Cd2+ ions, on mitochondrial membranes. The experiments showed that heavy metals are one of the most dangerous sources of environmental pollution, and that they have a strong genotoxic, tumo...

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Main Authors: Tojikulova Oysora, Asrarov Muzaffar, Bazarov Baxritdin, Rakhmatova Nigora, Turamkulov Shokir, Baratova Shoxsanam
Format: Article
Language:English
Published: EDP Sciences 2025-01-01
Series:BIO Web of Conferences
Online Access:https://www.bio-conferences.org/articles/bioconf/pdf/2025/24/bioconf_afe2024_02016.pdf
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author Tojikulova Oysora
Asrarov Muzaffar
Bazarov Baxritdin
Rakhmatova Nigora
Turamkulov Shokir
Baratova Shoxsanam
author_facet Tojikulova Oysora
Asrarov Muzaffar
Bazarov Baxritdin
Rakhmatova Nigora
Turamkulov Shokir
Baratova Shoxsanam
author_sort Tojikulova Oysora
collection DOAJ
description This article describes the results of a study conducted on rats on the effects of heavy metal salts, including Cd2+ ions, on mitochondrial membranes. The experiments showed that heavy metals are one of the most dangerous sources of environmental pollution, and that they have a strong genotoxic, tumor-causing and cytotoxic effect when ingested. Cd2+ poisoning occurs in the metallurgical industry through inhalation of atmospheric air, consumption of contaminated food and water, and cigarette smoke. The studies showed that the studied heavy metal salts, Cd2+ ions, negatively affect the structure of the mitochondrial membrane, increasing the passive permeability of the membrane for monovalent H+, K+ and Na+ cations.
format Article
id doaj-art-2b4ad69bb77f4c99ad5b7cefc4b38b9f
institution OA Journals
issn 2117-4458
language English
publishDate 2025-01-01
publisher EDP Sciences
record_format Article
series BIO Web of Conferences
spelling doaj-art-2b4ad69bb77f4c99ad5b7cefc4b38b9f2025-08-20T01:53:30ZengEDP SciencesBIO Web of Conferences2117-44582025-01-011730201610.1051/bioconf/202517302016bioconf_afe2024_02016The effect of Cd2+ ions on the passive permeability of the mitochondrial membrane of liver cell of RatsTojikulova Oysora0Asrarov Muzaffar1Bazarov Baxritdin2Rakhmatova Nigora3Turamkulov Shokir4Baratova Shoxsanam5Samarkand State University named after Sharof RashidovResearch Institute of Biophysics and Biochemistry under the National University of UzbekistanSamarkand State University named after Sharof RashidovSamarkand State University named after Sharof RashidovSamarkand State University named after Sharof RashidovKarshi State UniversityThis article describes the results of a study conducted on rats on the effects of heavy metal salts, including Cd2+ ions, on mitochondrial membranes. The experiments showed that heavy metals are one of the most dangerous sources of environmental pollution, and that they have a strong genotoxic, tumor-causing and cytotoxic effect when ingested. Cd2+ poisoning occurs in the metallurgical industry through inhalation of atmospheric air, consumption of contaminated food and water, and cigarette smoke. The studies showed that the studied heavy metal salts, Cd2+ ions, negatively affect the structure of the mitochondrial membrane, increasing the passive permeability of the membrane for monovalent H+, K+ and Na+ cations.https://www.bio-conferences.org/articles/bioconf/pdf/2025/24/bioconf_afe2024_02016.pdf
spellingShingle Tojikulova Oysora
Asrarov Muzaffar
Bazarov Baxritdin
Rakhmatova Nigora
Turamkulov Shokir
Baratova Shoxsanam
The effect of Cd2+ ions on the passive permeability of the mitochondrial membrane of liver cell of Rats
BIO Web of Conferences
title The effect of Cd2+ ions on the passive permeability of the mitochondrial membrane of liver cell of Rats
title_full The effect of Cd2+ ions on the passive permeability of the mitochondrial membrane of liver cell of Rats
title_fullStr The effect of Cd2+ ions on the passive permeability of the mitochondrial membrane of liver cell of Rats
title_full_unstemmed The effect of Cd2+ ions on the passive permeability of the mitochondrial membrane of liver cell of Rats
title_short The effect of Cd2+ ions on the passive permeability of the mitochondrial membrane of liver cell of Rats
title_sort effect of cd2 ions on the passive permeability of the mitochondrial membrane of liver cell of rats
url https://www.bio-conferences.org/articles/bioconf/pdf/2025/24/bioconf_afe2024_02016.pdf
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