The effect of Cd2+ ions on the passive permeability of the mitochondrial membrane of liver cell of Rats

This article describes the results of a study conducted on rats on the effects of heavy metal salts, including Cd2+ ions, on mitochondrial membranes. The experiments showed that heavy metals are one of the most dangerous sources of environmental pollution, and that they have a strong genotoxic, tumo...

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Bibliographic Details
Main Authors: Tojikulova Oysora, Asrarov Muzaffar, Bazarov Baxritdin, Rakhmatova Nigora, Turamkulov Shokir, Baratova Shoxsanam
Format: Article
Language:English
Published: EDP Sciences 2025-01-01
Series:BIO Web of Conferences
Online Access:https://www.bio-conferences.org/articles/bioconf/pdf/2025/24/bioconf_afe2024_02016.pdf
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Summary:This article describes the results of a study conducted on rats on the effects of heavy metal salts, including Cd2+ ions, on mitochondrial membranes. The experiments showed that heavy metals are one of the most dangerous sources of environmental pollution, and that they have a strong genotoxic, tumor-causing and cytotoxic effect when ingested. Cd2+ poisoning occurs in the metallurgical industry through inhalation of atmospheric air, consumption of contaminated food and water, and cigarette smoke. The studies showed that the studied heavy metal salts, Cd2+ ions, negatively affect the structure of the mitochondrial membrane, increasing the passive permeability of the membrane for monovalent H+, K+ and Na+ cations.
ISSN:2117-4458