High risk of Pseudomonas aeruginosa infection in patients attending public hospitals in Sokoto, Nigeria
Background: Pseudomonas aeruginosa is a well-known opportunistic pathogen associated with various healthcare infections. This study investigated the prevalence of P. aeruginosa in patients attending Specialist Hospital and Maryam Abacha Women and Children Hospital in Sokoto, Nigeria and determine ri...
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Elsevier
2025-03-01
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| Series: | The Microbe |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2950194625000391 |
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| author | Abdurrahman Hassan Jibril Hassan Bawa Kabiru Mohammed Abdulrazak Nuhu Abdulbariu Ogirima Uhuami |
| author_facet | Abdurrahman Hassan Jibril Hassan Bawa Kabiru Mohammed Abdulrazak Nuhu Abdulbariu Ogirima Uhuami |
| author_sort | Abdurrahman Hassan Jibril |
| collection | DOAJ |
| description | Background: Pseudomonas aeruginosa is a well-known opportunistic pathogen associated with various healthcare infections. This study investigated the prevalence of P. aeruginosa in patients attending Specialist Hospital and Maryam Abacha Women and Children Hospital in Sokoto, Nigeria and determine risk factors that could be associated with infection. Methodology: Cross-sectional study approach was used to collect 204 clinical samples from patients attending these hospitals. Samples were processed using culture, biochemical, and PCR. Results: The overall prevalence of P. aeruginosa was found to be 12.8 %. Samples from wound and ear swab showed statistically significant higher prevalence of 7.8 % (16/204) and 3.4 % (7/204) respectively (χ2= 12.70, p = 0.013), while no isolate was detected in swab collected from eye and throat. Males had a higher prevalence (15.3 %) compared to females (10.4 %), though the difference was not statistically significant (χ2= 1.112, p value = 0.29). Notably, inpatients were at a significantly higher risk of infection P. aerugionsa (OR: 1.94 p = 0.0109). In addition, females, rural residents, and patients on antibiotic therapy for less than one week were associated with a decreased risk of infection. Logistic regression analysis further underscored the association between inpatient status and increased infection risk, while short-term antibiotic use appeared to decrease the likelihood of P. aeruginosa infection. Conclusion: The study highlights the need for stringent infection control measures, particularly in wound care and among inpatients. These findings are essential for healthcare providers and policymakers in developing targeted interventions to mitigate the impact of P. aeruginosa infections in Nigerian hospitals. |
| format | Article |
| id | doaj-art-2b494412eb6245b2afd1bf61c1ecee40 |
| institution | DOAJ |
| issn | 2950-1946 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | The Microbe |
| spelling | doaj-art-2b494412eb6245b2afd1bf61c1ecee402025-08-20T02:51:36ZengElsevierThe Microbe2950-19462025-03-01610027110.1016/j.microb.2025.100271High risk of Pseudomonas aeruginosa infection in patients attending public hospitals in Sokoto, NigeriaAbdurrahman Hassan Jibril0Hassan Bawa1Kabiru Mohammed2Abdulrazak Nuhu3Abdulbariu Ogirima Uhuami4Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, Usmanu Danfodiyo University Sokoto, Nigeria; Center for Advanced Medical Research and Training, Usmanu Danfodiyo University Sokoto, Nigeria; Corresponding author at: Department of Veterinary Public Health and Preventive Medicine, Faculty of Veterinary Medicine, Usmanu Danfodiyo University Sokoto, Nigeria.Department of Medical Microbiology, School of Medical Laboratory Science, Usmanu Danfodiyo University Sokoto, Nigeria; Medical Laboratory Council of Nigeria, Sokoto Zonal Office, NigeriaDepartment of Medical Microbiology, School of Medical Laboratory Science, Usmanu Danfodiyo University Sokoto, NigeriaDepartment of Medical Microbiology, School of Medical Laboratory Science, Usmanu Danfodiyo University Sokoto, NigeriaCenter for Advanced Medical Research and Training, Usmanu Danfodiyo University Sokoto, Nigeria; Department of Veterinary Microbiology, Usmanu Danfodiyo University Sokoto, Faculty of Veterinary Medicine, NigeriaBackground: Pseudomonas aeruginosa is a well-known opportunistic pathogen associated with various healthcare infections. This study investigated the prevalence of P. aeruginosa in patients attending Specialist Hospital and Maryam Abacha Women and Children Hospital in Sokoto, Nigeria and determine risk factors that could be associated with infection. Methodology: Cross-sectional study approach was used to collect 204 clinical samples from patients attending these hospitals. Samples were processed using culture, biochemical, and PCR. Results: The overall prevalence of P. aeruginosa was found to be 12.8 %. Samples from wound and ear swab showed statistically significant higher prevalence of 7.8 % (16/204) and 3.4 % (7/204) respectively (χ2= 12.70, p = 0.013), while no isolate was detected in swab collected from eye and throat. Males had a higher prevalence (15.3 %) compared to females (10.4 %), though the difference was not statistically significant (χ2= 1.112, p value = 0.29). Notably, inpatients were at a significantly higher risk of infection P. aerugionsa (OR: 1.94 p = 0.0109). In addition, females, rural residents, and patients on antibiotic therapy for less than one week were associated with a decreased risk of infection. Logistic regression analysis further underscored the association between inpatient status and increased infection risk, while short-term antibiotic use appeared to decrease the likelihood of P. aeruginosa infection. Conclusion: The study highlights the need for stringent infection control measures, particularly in wound care and among inpatients. These findings are essential for healthcare providers and policymakers in developing targeted interventions to mitigate the impact of P. aeruginosa infections in Nigerian hospitals.http://www.sciencedirect.com/science/article/pii/S2950194625000391Pseudomonas aeruginosaOpportunistic pathogensHealthcare InfectionCross-Sectional StudyNigeria |
| spellingShingle | Abdurrahman Hassan Jibril Hassan Bawa Kabiru Mohammed Abdulrazak Nuhu Abdulbariu Ogirima Uhuami High risk of Pseudomonas aeruginosa infection in patients attending public hospitals in Sokoto, Nigeria The Microbe Pseudomonas aeruginosa Opportunistic pathogens Healthcare Infection Cross-Sectional Study Nigeria |
| title | High risk of Pseudomonas aeruginosa infection in patients attending public hospitals in Sokoto, Nigeria |
| title_full | High risk of Pseudomonas aeruginosa infection in patients attending public hospitals in Sokoto, Nigeria |
| title_fullStr | High risk of Pseudomonas aeruginosa infection in patients attending public hospitals in Sokoto, Nigeria |
| title_full_unstemmed | High risk of Pseudomonas aeruginosa infection in patients attending public hospitals in Sokoto, Nigeria |
| title_short | High risk of Pseudomonas aeruginosa infection in patients attending public hospitals in Sokoto, Nigeria |
| title_sort | high risk of pseudomonas aeruginosa infection in patients attending public hospitals in sokoto nigeria |
| topic | Pseudomonas aeruginosa Opportunistic pathogens Healthcare Infection Cross-Sectional Study Nigeria |
| url | http://www.sciencedirect.com/science/article/pii/S2950194625000391 |
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