Multi-omics study reveals differential expression and phosphorylation of autophagy-related proteins in autism spectrum disorder
Abstract Our multi-omics study investigated the molecular mechanisms underlying autism spectrum disorder (ASD) using Shank3 Δ4–22 and Cntnap2 −/− mouse models. Through global- and phospho- proteomics of the mouse cortex, we focused on shared molecular changes and found that autophagy was particularl...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-03-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-025-95860-8 |
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