Laboratory safety evaluation at the Ethiopian Public Health Institute, 2018-2019
# Background In 2015, Ethiopia designated rabies as a priority zoonotic disease. Challenges in rabies diagnostic capacity, including laboratory safety, were identified in 2016. As a pilot evaluation, the national rabies laboratory in Ethiopia (EPHI) was chosen to participate in an evaluation of necr...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Inishmore Laser Scientific Publishing Ltd
2021-03-01
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| Series: | Journal of Global Health Reports |
| Online Access: | https://doi.org/10.29392/001c.19039 |
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| author | Stephanie Ringler Emily G. Pieracci Sylvia Murphy Asefa Deressa Fatuma Yassin Bushra Theresa Kanter Getnet Yimer Lillian A. Orciari Mary Reynolds Lauren Greenberg |
| author_facet | Stephanie Ringler Emily G. Pieracci Sylvia Murphy Asefa Deressa Fatuma Yassin Bushra Theresa Kanter Getnet Yimer Lillian A. Orciari Mary Reynolds Lauren Greenberg |
| author_sort | Stephanie Ringler |
| collection | DOAJ |
| description | # Background
In 2015, Ethiopia designated rabies as a priority zoonotic disease. Challenges in rabies diagnostic capacity, including laboratory safety, were identified in 2016. As a pilot evaluation, the national rabies laboratory in Ethiopia (EPHI) was chosen to participate in an evaluation of necropsy laboratory facilities and procedures which was conducted over two years. This evaluation identified areas for improvement that strengthening would enhance safety in the laboratory environment. Process changes, specifically in cleaning procedures, will decrease the likelihood of cross contamination and improve precision of testing.
# Methods
This evaluation consisted of two sections: a 38-question verbal interview and an observational evaluation of necropsy laboratory practice. In March 2018, we evaluated EPHI’s laboratory biosafety procedures, and the laboratory technicians’ knowledge, practices, and attitudes in the animal necropsy laboratory before CDC-led laboratory trainings (September and December 2018). A post-training evaluation was conducted in March 2019.
# Results
Safety compliance scores in 2019 were noticeably increased from 2018. Interview scores increased from 57% to 91% and laboratory observation scores increased from 74% to 91%.
# Conclusion
This evaluation revealed that a necropsy laboratory assessment could be a valuable tool for understanding challenges faced by laboratories performing rabies diagnosis in Ethiopia. Assessment materials help to identify on-going challenges as well as areas of improvement in a systematic manner. In the future, this assessment could be used as a model for labs performing rabies diagnosis in a decentralized system. Additional rabies laboratories are anticipated to stand up throughout Ethiopia and laboratory assessments based on this methodology could provide valuable insights into how to mitigate risks. |
| format | Article |
| id | doaj-art-2b424d3cd0b94bcbbcb53e8ef4489af5 |
| institution | DOAJ |
| issn | 2399-1623 |
| language | English |
| publishDate | 2021-03-01 |
| publisher | Inishmore Laser Scientific Publishing Ltd |
| record_format | Article |
| series | Journal of Global Health Reports |
| spelling | doaj-art-2b424d3cd0b94bcbbcb53e8ef4489af52025-08-20T02:40:06ZengInishmore Laser Scientific Publishing LtdJournal of Global Health Reports2399-16232021-03-01510.29392/001c.19039Laboratory safety evaluation at the Ethiopian Public Health Institute, 2018-2019Stephanie RinglerEmily G. PieracciSylvia MurphyAsefa DeressaFatuma Yassin BushraTheresa KanterGetnet YimerLillian A. OrciariMary ReynoldsLauren Greenberg# Background In 2015, Ethiopia designated rabies as a priority zoonotic disease. Challenges in rabies diagnostic capacity, including laboratory safety, were identified in 2016. As a pilot evaluation, the national rabies laboratory in Ethiopia (EPHI) was chosen to participate in an evaluation of necropsy laboratory facilities and procedures which was conducted over two years. This evaluation identified areas for improvement that strengthening would enhance safety in the laboratory environment. Process changes, specifically in cleaning procedures, will decrease the likelihood of cross contamination and improve precision of testing. # Methods This evaluation consisted of two sections: a 38-question verbal interview and an observational evaluation of necropsy laboratory practice. In March 2018, we evaluated EPHI’s laboratory biosafety procedures, and the laboratory technicians’ knowledge, practices, and attitudes in the animal necropsy laboratory before CDC-led laboratory trainings (September and December 2018). A post-training evaluation was conducted in March 2019. # Results Safety compliance scores in 2019 were noticeably increased from 2018. Interview scores increased from 57% to 91% and laboratory observation scores increased from 74% to 91%. # Conclusion This evaluation revealed that a necropsy laboratory assessment could be a valuable tool for understanding challenges faced by laboratories performing rabies diagnosis in Ethiopia. Assessment materials help to identify on-going challenges as well as areas of improvement in a systematic manner. In the future, this assessment could be used as a model for labs performing rabies diagnosis in a decentralized system. Additional rabies laboratories are anticipated to stand up throughout Ethiopia and laboratory assessments based on this methodology could provide valuable insights into how to mitigate risks.https://doi.org/10.29392/001c.19039 |
| spellingShingle | Stephanie Ringler Emily G. Pieracci Sylvia Murphy Asefa Deressa Fatuma Yassin Bushra Theresa Kanter Getnet Yimer Lillian A. Orciari Mary Reynolds Lauren Greenberg Laboratory safety evaluation at the Ethiopian Public Health Institute, 2018-2019 Journal of Global Health Reports |
| title | Laboratory safety evaluation at the Ethiopian Public Health Institute, 2018-2019 |
| title_full | Laboratory safety evaluation at the Ethiopian Public Health Institute, 2018-2019 |
| title_fullStr | Laboratory safety evaluation at the Ethiopian Public Health Institute, 2018-2019 |
| title_full_unstemmed | Laboratory safety evaluation at the Ethiopian Public Health Institute, 2018-2019 |
| title_short | Laboratory safety evaluation at the Ethiopian Public Health Institute, 2018-2019 |
| title_sort | laboratory safety evaluation at the ethiopian public health institute 2018 2019 |
| url | https://doi.org/10.29392/001c.19039 |
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