MYBL2 promotes cell proliferation and inhibits cell apoptosis via PI3K/AKT and BCL2/BAX/Cleaved-caspase-3 signaling pathway in gastric cancer cells

MYBL2 promotes cell proliferation and inhibits cell apoptosis via PI3K/AKT and BCL2/BAX/Cleaved-caspase-3 signaling pathway in gastric cancer cells

Abstract The transcription factor MYB proto-oncogene like 2 (MYBL2) has been reported to be involved in the occurrence and development of various tumors, however, its role in gastric cancer (GC) remains to be elucidated. In this study, the Kaplan-Meier plotter was used to evaluate the prognostic val...

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Bibliographic Details
Main Authors: Jingya Chen, Zhenglei Ji, Di Wu, Siyang Wei, Wanjing Zhu, Guisen Peng, Mingjie Hu, Yunli Zhao, Huazhang Wu
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
MYBL2
Cell proliferation
Cell apoptosis
PI3K/AKT signaling pathway
Gastric cancer
Online Access:https://doi.org/10.1038/s41598-025-93022-4
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