Determination of Ruboxistaurin analysis in rat plasma utilizing LC–MS/MS technique

Determination of Ruboxistaurin analysis in rat plasma utilizing LC–MS/MS technique

Background: Ruboxistaurin (RBX) used to treat retinopathy in diabetic patients which caused by microvascular damage and leakage which contributes to visual loss. There are no published studies on the use of liquid chromatography-tandem mass spectrometry for development and validation of a simple, se...

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Bibliographic Details
Main Authors: Bushra T. AlQuadeib, Fadilah S. Aleanizy, Fulwah Y. Alqahtani, Rehab A. Alshammari, Amal Aldarwesh, Ibrahim Alsarra
Format: Article
Language:English
Published: Springer 2023-04-01
Series:Saudi Pharmaceutical Journal
Subjects:
Ruboxistaurin
Validation
LC-MS/MS
Plasma
Rat
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016423000373
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