Upregulation of TREM2 expression in M2 macrophages promotes Brucella abortus chronic infection

Upregulation of TREM2 expression in M2 macrophages promotes Brucella abortus chronic infection

Brucella abortus (B.abortus) is a zoonotic bacterial pathogen that causes chronic host infections. The eradication of brucellosis using antibiotic therapy is often incomplete or slow. In a mouse model, the predominance of alternatively activated macrophages (also known as M2) plays an essential role...

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Bibliographic Details
Main Authors: Jingyu Wang, Zhirong Yan, Weiyu Zhang, Xiaofeng Liu, Jun Wang, Qisheng Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Immunology
Subjects:
Brucella abortus
TREM2
macrophages
chronic infection
proliferation
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1466520/full
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